RAFAEL
LEÓN MARTÍNEZ
Profesor asociado
Antonio
Cuadrado
Publications by the researcher in collaboration with Antonio Cuadrado (9)
2023
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KEAP1-NRF2 protein–protein interaction inhibitors: Design, pharmacological properties and therapeutic potential
Medicinal Research Reviews, Vol. 43, Núm. 1, pp. 237-287
2022
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Novel Series of Dual NRF2 Inducers and Selective MAO-B Inhibitors for the Treatment of Parkinson’s Disease
Antioxidants, Vol. 11, Núm. 2
2021
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Monoamine Oxidase Inhibitors: From Classic to New Clinical Approaches
Handbook of Experimental Pharmacology (Springer Science and Business Media Deutschland GmbH), pp. 229-259
2020
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Melatonin-sulforaphane hybrid ITH12674 attenuates glial response in vivo by blocking LPS binding to MD2 and receptor oligomerization
Pharmacological Research, Vol. 152
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Tuning melatonin receptor subtype selectivity in oxadiazolone-based analogues: Discovery of QR2 ligands and NRF2 activators with neurogenic properties
European Journal of Medicinal Chemistry, Vol. 190
2018
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Transcription factor NRF2 as a therapeutic target for chronic diseases: A systems medicine approach
Pharmacological Reviews, Vol. 70, Núm. 2, pp. 348-383
2017
2015
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Melatonin-sulforaphane hybrid ITH12674 induces neuroprotection in oxidative stress conditions by a 'drug-prodrug' mechanism of action
British Journal of Pharmacology, Vol. 172, Núm. 7, pp. 1807-1821
2014
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Neuroprotective effect of melatonin against ischemia is partially mediated by alpha-7 nicotinic receptor modulation and HO-1 overexpression
Journal of Pineal Research, Vol. 56, Núm. 2, pp. 204-212