RAFAEL
LEÓN MARTÍNEZ
Profesor asociado
University of Cambridge
Cambridge, Reino UnidoPublicacións en colaboración con investigadores/as de University of Cambridge (6)
2014
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Gram-scale enantioselective formal synthesis of morphine through an orthöpara oxidative phenolic coupling strategy
Angewandte Chemie - International Edition, Vol. 53, Núm. 49, pp. 13498-13501
2013
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Recent advances in the multitarget-directed ligands approach for the treatment of Alzheimer's disease
Medicinal Research Reviews, Vol. 33, Núm. 1, pp. 139-189
2011
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A step further towards multitarget drugs for Alzheimer and neuronal vascular diseases: Targeting the cholinergic system, amyloid-β aggregation and Ca2+dyshomeostasis
Current Medicinal Chemistry, Vol. 18, Núm. 4, pp. 552-576
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Catalytic enantioselective assembly of complex molecules containing embedded quaternary stereogenic centres from simple anisidine derivatives
Chemical Science, Vol. 2, Núm. 8, pp. 1487-1490
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Effects of novel tacripyrines ITH12117 and ITH12118 on rat vas deferens contractions, calcium transients and cholinesterase activity
European Journal of Pharmacology, Vol. 660, Núm. 2-3, pp. 411-419
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Elucidating the reaction mechanism of the benzoate oxidation pathway encoded aldehyde dehydrogenase from Burkholderia xenovorans LB400
Protein Science, Vol. 20, Núm. 6, pp. 1048-1059