Publications in collaboration with researchers from Universidad Autónoma de Madrid (64)

2024

  1. Discovery of a potent melatonin-based inhibitor of quinone reductase-2 with neuroprotective and neurogenic properties

    European Journal of Medicinal Chemistry, Vol. 277

  2. Innovative pathological network-based multitarget approaches for Alzheimer's disease treatment

    Medicinal Research Reviews

2023

  1. KEAP1-NRF2 protein–protein interaction inhibitors: Design, pharmacological properties and therapeutic potential

    Medicinal Research Reviews, Vol. 43, Núm. 1, pp. 237-287

2022

  1. Curcumin-piperlongumine hybrids with a multitarget profile elicit neuroprotection in in vitro models of oxidative stress and hyperphosphorylation

    Antioxidants, Vol. 11, Núm. 1

  2. Novel Series of Dual NRF2 Inducers and Selective MAO-B Inhibitors for the Treatment of Parkinson’s Disease

    Antioxidants, Vol. 11, Núm. 2

  3. Resveratrol-Based MTDLs to Stimulate Defensive and Regenerative Pathways and Block Early Events in Neurodegenerative Cascades

    Journal of Medicinal Chemistry, Vol. 65, Núm. 6, pp. 4727-4751

2021

  1. Bisavenathramide analogues as nrf2 inductors and neuroprotectors in in vitro models of oxidative stress and hyperphosphorylation

    Antioxidants, Vol. 10, Núm. 6

  2. Enhanced stability and bioactivity of natural anticancer topoisomerase i inhibitors through cyclodextrin complexation

    Pharmaceutics, Vol. 13, Núm. 10

  3. Monoamine Oxidase Inhibitors: From Classic to New Clinical Approaches

    Handbook of Experimental Pharmacology (Springer Science and Business Media Deutschland GmbH), pp. 229-259

2020

  1. Antioxidant, anti-inflammatory and neuroprotective profiles of novel 1,4-dihydropyridine derivatives for the treatment of alzheimer’s disease

    Antioxidants, Vol. 9, Núm. 8, pp. 1-20

  2. Aza-CGP37157-lipoic hybrids designed as novel Nrf2-inducers and antioxidants exert neuroprotection against oxidative stress and show neuroinflammation inhibitory properties

    Drug Development Research, Vol. 81, Núm. 3, pp. 283-294

  3. Melatonin-sulforaphane hybrid ITH12674 attenuates glial response in vivo by blocking LPS binding to MD2 and receptor oligomerization

    Pharmacological Research, Vol. 152

  4. NRF2 Regulation Processes as a Source of Potential Drug Targets against Neurodegenerative Diseases

    Biomolecules, Vol. 10, Núm. 6

  5. New Nrf2-inducer compound ITH12674 slows the progression of retinitis pigmentosa in the mouse model rd10

    Cellular Physiology and Biochemistry, Vol. 54, Núm. 1, pp. 142-159

  6. Tuning melatonin receptor subtype selectivity in oxadiazolone-based analogues: Discovery of QR2 ligands and NRF2 activators with neurogenic properties

    European Journal of Medicinal Chemistry, Vol. 190

  7. When it comes to an end: Oxidative stress crosstalk with protein aggregation and neuroinflammation induce neurodegeneration

    Antioxidants, Vol. 9, Núm. 8, pp. 1-34

2019

  1. Nrf2 plays a protective role against intravascular hemolysis-mediated acute kidney injury

    Frontiers in Pharmacology, Vol. 10

  2. Pharmacological doses of melatonin impede cognitive decline in tau-related Alzheimer models, once tauopathy is initiated, by restoring the autophagic flux

    Journal of Pineal Research, Vol. 67, Núm. 1

  3. The angiotensin-(1-7)/Mas receptor axis protects from endothelial cell senescence via klotho and Nrf2 activation

    Aging Cell, Vol. 18, Núm. 3

2018

  1. The APPswe/PS1A246E mutations in an astrocytic cell line leads to increased vulnerability to oxygen and glucose deprivation, Ca 2+ dysregulation, and mitochondrial abnormalities

    Journal of Neurochemistry, Vol. 145, Núm. 2, pp. 170-182