JOSÉ ANTONIO ESCARIO GARCÍA-TREVIJANO-rekin lankidetzan egindako argitalpenak (15)

2022

  1. 5-Nitroindazole-based compounds: further studies for activity optimization as anti-Trypanosoma cruzi agents

    Acta Tropica, Vol. 234

  2. Thio- and selenosemicarbazones as antiprotozoal agents against Trypanosoma cruzi and Trichomonas vaginalis

    Journal of enzyme inhibition and medicinal chemistry, Vol. 37, Núm. 1, pp. 781-791

2021

  1. Promising hit compounds against resistant trichomoniasis: Synthesis and antiparasitic activity of 3-(ω-aminoalkoxy)-1-benzyl-5-nitroindazoles

    Bioorganic and Medicinal Chemistry Letters, Vol. 37

2020

  1. Activity profile of two 5-nitroindazole derivatives over the moderately drug-resistant Trypanosoma cruzi y strain (DTU TcII): In vitro and in vivo studies

    Parasitology, Vol. 147, Núm. 11, pp. 1216-1228

2018

  1. Antichagasic, Leishmanicidal, and Trichomonacidal Activity of 2-Benzyl-5-nitroindazole-Derived Amines

    ChemMedChem, Vol. 13, Núm. 12, pp. 1246-1259

  2. Experimental models in Chagas disease: a review of the methodologies applied for screening compounds against Trypanosoma cruzi

    Parasitology Research, Vol. 117, Núm. 11, pp. 3367-3380

2017

  1. Novel Imidazo[4,5-c][1,2,6]thiadiazine 2,2-dioxides as antiproliferative trypanosoma cruzi drugs: Computational screening from neural network, synthesis and in vivo biological properties

    European Journal of Medicinal Chemistry, Vol. 136, pp. 223-234

2016

  1. Antichagasic and trichomonacidal activity of 1-substituted 2-benzyl-5-nitroindazolin-3-ones and 3-alkoxy-2-benzyl-5-nitro-2H-indazoles

    European Journal of Medicinal Chemistry, Vol. 115, pp. 295-310

  2. Biological approaches to characterize the mode of action of two 5-nitroindazolinone prototypes on Trypanosoma cruzi bloodstream trypomastigotes

    Parasitology, Vol. 143, Núm. 11, pp. 1469-1478

2015

  1. Novel solid dispersions of benznidazole: Preparation, dissolution profile and biological evaluation as alternative antichagasic drug delivery system

    Experimental Parasitology, Vol. 149, pp. 84-91

2014

  1. Development of novel benznidazole formulations: Physicochemical characterization and in vivo evaluation on parasitemia reduction in Chagas disease

    International Journal of Pharmaceutics, Vol. 472, Núm. 1-2, pp. 110-117

  2. Further insights into biological evaluation of new anti-Trypanosoma cruzi 5-nitroindazoles

    Parasitology Research, Vol. 113, Núm. 3, pp. 1049-1056

  3. In vitro phenotypic screening of 7-chloro-4-amino(oxy)quinoline derivatives as putative anti-Trypanosoma cruzi agents

    Bioorganic and Medicinal Chemistry Letters, Vol. 24, Núm. 4, pp. 1209-1213

2013

  1. Selective activity of 2,4-diaryl-1,2,3,4-tetrahydroquinolines on Trypanosoma cruzi epimastigotes and amastigotes expressing β-galactosidase

    Bioorganic and Medicinal Chemistry Letters, Vol. 23, Núm. 17, pp. 4851-4856

2012

  1. Synthesis, biological evaluation and chemometric analysis of indazole derivatives. 1,2-Disubstituted 5-nitroindazolinones, new prototypes of antichagasic drug

    European Journal of Medicinal Chemistry, Vol. 58, pp. 214-227