CRISTINA ROSA
FONSECA BERZAL
Profesora ayudante doctora
![Foto de CRISTINA ROSA](/img/nophoto.png)
![Foto de Instituto de Química Médica](/img/noimage_org.png)
Instituto de Química Médica
Madrid, EspañaInstituto de Química Médica -ko ikertzaileekin lankidetzan egindako argitalpenak (13)
2023
-
Synthesis and Biophysical and Biological Studies of N-Phenylbenzamide Derivatives Targeting Kinetoplastid Parasites
Journal of Medicinal Chemistry, Vol. 66, Núm. 19, pp. 13452-13480
2022
2021
-
Promising hit compounds against resistant trichomoniasis: Synthesis and antiparasitic activity of 3-(ω-aminoalkoxy)-1-benzyl-5-nitroindazoles
Bioorganic and Medicinal Chemistry Letters, Vol. 37
2020
-
Activity profile of two 5-nitroindazole derivatives over the moderately drug-resistant Trypanosoma cruzi y strain (DTU TcII): In vitro and in vivo studies
Parasitology, Vol. 147, Núm. 11, pp. 1216-1228
2018
-
Antichagasic, Leishmanicidal, and Trichomonacidal Activity of 2-Benzyl-5-nitroindazole-Derived Amines
ChemMedChem, Vol. 13, Núm. 12, pp. 1246-1259
-
Experimental models in Chagas disease: a review of the methodologies applied for screening compounds against Trypanosoma cruzi
Parasitology Research, Vol. 117, Núm. 11, pp. 3367-3380
2017
-
New imidazole-based compounds active against Trypanosoma cruzi
Combinatorial Chemistry and High Throughput Screening, Vol. 20, Núm. 1, pp. 20-24
-
Novel Imidazo[4,5-c][1,2,6]thiadiazine 2,2-dioxides as antiproliferative trypanosoma cruzi drugs: Computational screening from neural network, synthesis and in vivo biological properties
European Journal of Medicinal Chemistry, Vol. 136, pp. 223-234
2016
-
Antichagasic and trichomonacidal activity of 1-substituted 2-benzyl-5-nitroindazolin-3-ones and 3-alkoxy-2-benzyl-5-nitro-2H-indazoles
European Journal of Medicinal Chemistry, Vol. 115, pp. 295-310
-
Biological approaches to characterize the mode of action of two 5-nitroindazolinone prototypes on Trypanosoma cruzi bloodstream trypomastigotes
Parasitology, Vol. 143, Núm. 11, pp. 1469-1478
2015
-
Novel solid dispersions of benznidazole: Preparation, dissolution profile and biological evaluation as alternative antichagasic drug delivery system
Experimental Parasitology, Vol. 149, pp. 84-91
2014
-
Development of novel benznidazole formulations: Physicochemical characterization and in vivo evaluation on parasitemia reduction in Chagas disease
International Journal of Pharmaceutics, Vol. 472, Núm. 1-2, pp. 110-117
2012
-
Synthesis, biological evaluation and chemometric analysis of indazole derivatives. 1,2-Disubstituted 5-nitroindazolinones, new prototypes of antichagasic drug
European Journal of Medicinal Chemistry, Vol. 58, pp. 214-227