CRISTINA ROSA
FONSECA BERZAL
Profesora permanente laboral
Publicaciones (23) Publicaciones de CRISTINA ROSA FONSECA BERZAL
2024
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Development, Characterization, and Cellular Toxicity Evaluation of Solid Dispersion-Loaded Hydrogel Based on Indomethacin
Polymers, Vol. 16, Núm. 15
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Microbial Matryoshka: Addressing the Relationship between Pathogenic Flagellated Protozoans and Their RNA Viral Endosymbionts (Family Totiviridae)
Veterinary Sciences, Vol. 11, Núm. 7
2023
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Synthesis and Biophysical and Biological Studies of N-Phenylbenzamide Derivatives Targeting Kinetoplastid Parasites
Journal of Medicinal Chemistry, Vol. 66, Núm. 19, pp. 13452-13480
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Trichomonas vaginalis: diagnóstico de una infección de transmisión sexual olvidada
Anales de la Real Academia Nacional de Farmacia, Vol. 89, Núm. 2, pp. 135-147
2022
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5-Nitroindazole-based compounds: further studies for activity optimization as anti-Trypanosoma cruzi agents
Acta Tropica, Vol. 234
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Thio- and selenosemicarbazones as antiprotozoal agents against Trypanosoma cruzi and Trichomonas vaginalis
Journal of enzyme inhibition and medicinal chemistry, Vol. 37, Núm. 1, pp. 781-791
2021
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Promising hit compounds against resistant trichomoniasis: Synthesis and antiparasitic activity of 3-(ω-aminoalkoxy)-1-benzyl-5-nitroindazoles
Bioorganic and Medicinal Chemistry Letters, Vol. 37
2020
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Activity profile of two 5-nitroindazole derivatives over the moderately drug-resistant Trypanosoma cruzi y strain (DTU TcII): In vitro and in vivo studies
Parasitology, Vol. 147, Núm. 11, pp. 1216-1228
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Efficacy of novel pyrazolone phosphodiesterase inhibitors in experimental mouse models of Trypanosoma cruzi
Antimicrobial Agents and Chemotherapy, Vol. 64, Núm. 9
2019
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Imidazole derivatives as promising agents for the treatment of Chagas disease
Antimicrobial Agents and Chemotherapy, Vol. 63, Núm. 4
2018
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Antichagasic, Leishmanicidal, and Trichomonacidal Activity of 2-Benzyl-5-nitroindazole-Derived Amines
ChemMedChem, Vol. 13, Núm. 12, pp. 1246-1259
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Experimental models in Chagas disease: a review of the methodologies applied for screening compounds against Trypanosoma cruzi
Parasitology Research, Vol. 117, Núm. 11, pp. 3367-3380
2017
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New imidazole-based compounds active against Trypanosoma cruzi
Combinatorial Chemistry and High Throughput Screening, Vol. 20, Núm. 1, pp. 20-24
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Novel Imidazo[4,5-c][1,2,6]thiadiazine 2,2-dioxides as antiproliferative trypanosoma cruzi drugs: Computational screening from neural network, synthesis and in vivo biological properties
European Journal of Medicinal Chemistry, Vol. 136, pp. 223-234
2016
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Antichagasic and trichomonacidal activity of 1-substituted 2-benzyl-5-nitroindazolin-3-ones and 3-alkoxy-2-benzyl-5-nitro-2H-indazoles
European Journal of Medicinal Chemistry, Vol. 115, pp. 295-310
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Biological approaches to characterize the mode of action of two 5-nitroindazolinone prototypes on Trypanosoma cruzi bloodstream trypomastigotes
Parasitology, Vol. 143, Núm. 11, pp. 1469-1478
2015
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Novel solid dispersions of benznidazole: Preparation, dissolution profile and biological evaluation as alternative antichagasic drug delivery system
Experimental Parasitology, Vol. 149, pp. 84-91
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Trypanocidal Activity of Long Chain Diamines and Aminoalcohols
Molecules, Vol. 20, Núm. 6, pp. 11554-11568
2014
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Development of novel benznidazole formulations: Physicochemical characterization and in vivo evaluation on parasitemia reduction in Chagas disease
International Journal of Pharmaceutics, Vol. 472, Núm. 1-2, pp. 110-117
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Further insights into biological evaluation of new anti-Trypanosoma cruzi 5-nitroindazoles
Parasitology Research, Vol. 113, Núm. 3, pp. 1049-1056