JOSÉ ANTONIO
ESCARIO GARCÍA-TREVIJANO
Profesor emérito
ALICIA
GÓMEZ BARRIO
Catedrática de universidad
ALICIA GÓMEZ BARRIO-rekin lankidetzan egindako argitalpenak (64)
2022
-
5-Nitroindazole-based compounds: further studies for activity optimization as anti-Trypanosoma cruzi agents
Acta Tropica, Vol. 234
-
Thio- and selenosemicarbazones as antiprotozoal agents against Trypanosoma cruzi and Trichomonas vaginalis
Journal of enzyme inhibition and medicinal chemistry, Vol. 37, Núm. 1, pp. 781-791
2021
-
Promising hit compounds against resistant trichomoniasis: Synthesis and antiparasitic activity of 3-(ω-aminoalkoxy)-1-benzyl-5-nitroindazoles
Bioorganic and Medicinal Chemistry Letters, Vol. 37
2020
-
Activity profile of two 5-nitroindazole derivatives over the moderately drug-resistant Trypanosoma cruzi y strain (DTU TcII): In vitro and in vivo studies
Parasitology, Vol. 147, Núm. 11, pp. 1216-1228
2018
-
Antichagasic, Leishmanicidal, and Trichomonacidal Activity of 2-Benzyl-5-nitroindazole-Derived Amines
ChemMedChem, Vol. 13, Núm. 12, pp. 1246-1259
-
Drug repositioning for novel antitrichomonas from known antiprotozoan drugs using hierarchical screening
Future Medicinal Chemistry, Vol. 10, Núm. 8, pp. 863-878
-
Experimental models in Chagas disease: a review of the methodologies applied for screening compounds against Trypanosoma cruzi
Parasitology Research, Vol. 117, Núm. 11, pp. 3367-3380
2017
-
Novel Imidazo[4,5-c][1,2,6]thiadiazine 2,2-dioxides as antiproliferative trypanosoma cruzi drugs: Computational screening from neural network, synthesis and in vivo biological properties
European Journal of Medicinal Chemistry, Vol. 136, pp. 223-234
2016
-
Antichagasic and trichomonacidal activity of 1-substituted 2-benzyl-5-nitroindazolin-3-ones and 3-alkoxy-2-benzyl-5-nitro-2H-indazoles
European Journal of Medicinal Chemistry, Vol. 115, pp. 295-310
-
Biological approaches to characterize the mode of action of two 5-nitroindazolinone prototypes on Trypanosoma cruzi bloodstream trypomastigotes
Parasitology, Vol. 143, Núm. 11, pp. 1469-1478
-
In vitro trichomonacidal activity and preliminary in silico chemometric studies of 5-nitroindazolin-3-one and 3-alkoxy-5-nitroindazole derivatives
Parasitology, Vol. 143, Núm. 1, pp. 34-40
2015
-
Bond-based bilinear indices for computational discovery of novel trypanosomicidal drug-like compounds through virtual screening
European Journal of Medicinal Chemistry, Vol. 96, pp. 238-244
-
Novel solid dispersions of benznidazole: Preparation, dissolution profile and biological evaluation as alternative antichagasic drug delivery system
Experimental Parasitology, Vol. 149, pp. 84-91
-
Sequestration of host-CD59 as potential immune evasion strategy of Trichomonas vaginalis
Acta Tropica, Vol. 149, pp. 1-7
-
Synthesis and in vitro and in vivo biological evaluation of substituted nitroquinoxalin-2-ones and 2,3-diones as novel trichomonacidal agents
European Journal of Medicinal Chemistry, Vol. 94, pp. 276-283
2014
-
A sequential procedure for rapid and accurate identification of putative trichomonacidal agents
Journal of Microbiological Methods, Vol. 105, pp. 162-167
-
Antiprotozoan lead discovery by aligning dry and wet screening: Prediction, synthesis, and biological assay of novel quinoxalinones
Bioorganic and Medicinal Chemistry, Vol. 22, Núm. 5, pp. 1568-1585
-
Determination of internal transcribed spacer regions (ITS) in Trichomonas vaginalis isolates and differentiation among Trichomonas species
Parasitology International, Vol. 63, Núm. 2, pp. 427-431
-
Development of novel benznidazole formulations: Physicochemical characterization and in vivo evaluation on parasitemia reduction in Chagas disease
International Journal of Pharmaceutics, Vol. 472, Núm. 1-2, pp. 110-117
-
Further insights into biological evaluation of new anti-Trypanosoma cruzi 5-nitroindazoles
Parasitology Research, Vol. 113, Núm. 3, pp. 1049-1056