JOSÉ ANTONIO
ESCARIO GARCÍA-TREVIJANO
Profesor emérito
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Universidad Central de Las Villas
Santa Clara, CubaUniversidad Central de Las Villas-ko ikertzaileekin lankidetzan egindako argitalpenak (19)
2018
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Antichagasic, Leishmanicidal, and Trichomonacidal Activity of 2-Benzyl-5-nitroindazole-Derived Amines
ChemMedChem, Vol. 13, Núm. 12, pp. 1246-1259
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Drug repositioning for novel antitrichomonas from known antiprotozoan drugs using hierarchical screening
Future Medicinal Chemistry, Vol. 10, Núm. 8, pp. 863-878
2015
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Bond-based bilinear indices for computational discovery of novel trypanosomicidal drug-like compounds through virtual screening
European Journal of Medicinal Chemistry, Vol. 96, pp. 238-244
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Synthesis and in vitro and in vivo biological evaluation of substituted nitroquinoxalin-2-ones and 2,3-diones as novel trichomonacidal agents
European Journal of Medicinal Chemistry, Vol. 94, pp. 276-283
2014
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A sequential procedure for rapid and accurate identification of putative trichomonacidal agents
Journal of Microbiological Methods, Vol. 105, pp. 162-167
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Antiprotozoan lead discovery by aligning dry and wet screening: Prediction, synthesis, and biological assay of novel quinoxalinones
Bioorganic and Medicinal Chemistry, Vol. 22, Núm. 5, pp. 1568-1585
2012
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Identification In Silico and In Vitro of Novel Trypanosomicidal Drug-Like Compounds
Chemical Biology and Drug Design, Vol. 80, Núm. 1, pp. 38-45
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Synthesis, biological evaluation and chemometric analysis of indazole derivatives. 1,2-Disubstituted 5-nitroindazolinones, new prototypes of antichagasic drug
European Journal of Medicinal Chemistry, Vol. 58, pp. 214-227
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Validation of a modified fluorimetric assay for the screening of trichomonacidal drugs
Memorias do Instituto Oswaldo Cruz, Vol. 107, Núm. 5, pp. 637-643
2011
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Ligand-based discovery of novel trypanosomicidal drug-like compounds: In silico identification and experimental support
European Journal of Medicinal Chemistry, Vol. 46, Núm. 8, pp. 3324-3330
2009
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Discovery of novel trichomonacidals using LDA-driven QSAR models and bond-based bilinear indices as molecular descriptors
QSAR and Combinatorial Science, Vol. 28, Núm. 1, pp. 9-26
2008
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Bond-based linear indices in QSAR: Computational discovery of novel anti-trichomonal compounds
Journal of Computer-Aided Molecular Design, Vol. 22, Núm. 8, pp. 523-540
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New antitrichomonal drug-like chemicals selected by bond (edge)-based TOMOCOMD-CARDD descriptors
Journal of Biomolecular Screening, Vol. 13, Núm. 8, pp. 785-794
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Saponinas esteroidales de la planta Agave brittoniana (Agavaceae) con actividad contra el parásito Trichomona vaginalis
Revista de Biologia Tropical, Vol. 56, Núm. 4, pp. 1645-1652
2006
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New ligand-based approach for the discovery of antitrypanosomal compounds
Bioorganic and Medicinal Chemistry Letters, Vol. 16, Núm. 7, pp. 1898-1904
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Predicting antitrichomonal activity: A computational screening using atom-based bilinear indices and experimental proofs
Bioorganic and Medicinal Chemistry, Vol. 14, Núm. 19, pp. 6502-6524
2005
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A computer-based approach to the rational discovery of new trichomonacidal drugs by atom-type linear indices
Current Drug Discovery Technologies, Vol. 2, Núm. 4, pp. 245-265
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A linear discrimination analysis based virtual screening of trichomonacidal lead-like compounds: Outcomes of in silico studies supported by experimental results
Bioorganic and Medicinal Chemistry Letters, Vol. 15, Núm. 17, pp. 3838-3843
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A novel non-stochastic quadratic fingerprints-based approach for the 'in silico' discovery of new antitrypanosomal compounds
Bioorganic and Medicinal Chemistry, Vol. 13, Núm. 22, pp. 6264-6275