Publications (85) IRENE BRAVO OSUNA publications

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2025

  1. Disclosing long-term tolerance, efficacy and penetration properties of hyaluronic acid-coated latanoprost-loaded liposomes as chronic glaucoma therapy

    Journal of Controlled Release, Vol. 379, pp. 730-742

  2. Ketorolac, melatonin and latanoprost tri-loaded PLGA microspheres for neuroprotection in glaucoma

    Drug Delivery, Vol. 32, Núm. 1

  3. Multi-loaded PLGA microspheres as neuroretinal therapy in a chronic glaucoma animal model

    Drug Delivery and Translational Research, Vol. 15, Núm. 5, pp. 1660-1684

2024

  1. Chronic Glaucoma Induced in Rats by a Single Injection of Fibronectin-Loaded PLGA Microspheres: IOP-Dependent and IOP-Independent Neurodegeneration

    International Journal of Molecular Sciences, Vol. 25, Núm. 1

  2. Enhancing the hypotensive effect of latanoprost by combining synthetic phosphatidylcholine liposomes with hyaluronic acid and osmoprotective agents

    Drug Delivery and Translational Research, Vol. 14, Núm. 10, pp. 2804-2822

  3. Immune Analysis Using Vitreous Optical Coherence Tomography Imaging in Rats with Steroid-Induced Glaucoma

    Biomedicines, Vol. 12, Núm. 3

  4. Influence of sex on chronic steroid-induced glaucoma: 24-Weeks follow-up study in rats

    Experimental Eye Research, Vol. 238

  5. Smart biodegradable hydrogels: Drug-delivery platforms for treatment of chronic ophthalmic diseases affecting the back of the eye

    International Journal of Pharmaceutics, Vol. 649

  6. Useful Role of a New Generation of Dexamethasone, Vitamin E and Human Serum Albumin Microparticles in the Prevention of Excitotoxicity Injury in Retinal Ocular Diseases

    Pharmaceutics, Vol. 16, Núm. 3

2023

  1. Desarrollo de una formulación antiglaucomatosa tópica a partir de una lágrima artificial

    XVI Congreso SEFIG ( 16. 2023. Madrid): Libro de comunicaciones

  2. Microesferas biodegradables cargadas con dexametasona para el desarrollo de modelos animales de glaucoma crónico: la influencia de la adición de fibronectina por doble emulsión

    XVI Congreso SEFIG ( 16. 2023. Madrid): Libro de comunicaciones

  3. Microesferas biodegradables de liberación controlada de agentes antioxidantes y anti-inflamatorios como potencial terapia neuroprotectora para el glaucoma

    XVI Congreso SEFIG ( 16. 2023. Madrid): Libro de comunicaciones

2022

  1. Mimicking chronic glaucoma over 6 months with a single intracameral injection of dexamethasone/fibronectin-loaded PLGA microspheres

    Drug Delivery, Vol. 29, Núm. 1, pp. 2357-2374

  2. Novel Osmoprotective DOPC-DMPC Liposomes Loaded with Antihypertensive Drugs as Potential Strategy for Glaucoma Treatment

    Pharmaceutics, Vol. 14, Núm. 7

  3. Tunable degrees of neurodegeneration in rats based on microsphere-induced models of chronic glaucoma

    Scientific Reports, Vol. 12, Núm. 1

  4. Validation of a Rapid and Easy-to-Apply Method to Simultaneously Quantify Co-Loaded Dexamethasone and Melatonin PLGA Microspheres by HPLC-UV: Encapsulation Efficiency and In Vitro Release

    Pharmaceutics, Vol. 14, Núm. 2

2021

  1. A safe gdnf and gdnf/bdnf controlled delivery system improves migration in human retinal pigment epithelial cells and survival in retinal ganglion cells: Potential usefulness in degenerative retinal pathologies

    Pharmaceuticals, Vol. 14, Núm. 1, pp. 1-24

  2. Analysis of parainflammation in chronic glaucoma using vitreous-oct imaging

    Biomedicines, Vol. 9, Núm. 12

  3. Chronic glaucoma using biodegradable microspheres to induce intraocular pressure elevation. Six-month follow-up

    Biomedicines, Vol. 9, Núm. 6

  4. Co-delivery of glial cell–derived neurotrophic factor (GDNF) and tauroursodeoxycholic acid (TUDCA) from PLGA microspheres: potential combination therapy for retinal diseases

    Drug Delivery and Translational Research, Vol. 11, Núm. 2, pp. 566-580