MARÍA DOLORES
MARTÍN DE SAAVEDRA ÁLVAREZ DE URIBARRI
Profesora ayudante doctora
Manuela
García López
Publicaciones en las que colabora con Manuela García López (17)
2018
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The APPswe/PS1A246E mutations in an astrocytic cell line leads to increased vulnerability to oxygen and glucose deprivation, Ca 2+ dysregulation, and mitochondrial abnormalities
Journal of Neurochemistry, Vol. 145, Núm. 2, pp. 170-182
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Folic Acid Protects Against Glutamate-Induced Excitotoxicity in Hippocampal Slices Through a Mechanism that Implicates Inhibition of GSK-3β and iNOS
Molecular Neurobiology, Vol. 55, Núm. 2, pp. 1580-1589
2015
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Both creatine and its product phosphocreatine reduce oxidative stress and afford neuroprotection in an in vitro Parkinson’s model
ASN Neuro, Vol. 6, Núm. 6
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The modulation of NMDA receptors and l-arginine/nitric oxide pathway is implicated in the anti-immobility effect of creatine in the tail suspension test
Amino Acids, Vol. 47, Núm. 4, pp. 795-811
2014
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ITH12410/SC058: A new neuroprotective compound with potential in the treatment of Alzheimer's disease
ACS Chemical Neuroscience, Vol. 5, Núm. 9, pp. 770-775
2013
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Inhibition of calpain-regulated p35/cdk5 plays a central role in sildenafil-induced protection against chemical hypoxia produced by malonate
Biochimica et Biophysica Acta - Molecular Basis of Disease, Vol. 1832, Núm. 6, pp. 705-717
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Nrf2 participates in depressive disorders through an anti-inflammatory mechanism
Psychoneuroendocrinology, Vol. 38, Núm. 10, pp. 2010-2022
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Protective effect of creatine against 6-hydroxydopamine-induced cell death in human neuroblastoma SH-SY5Y cells: Involvement of intracellular signaling pathways
Neuroscience, Vol. 238, pp. 185-194
2012
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Galantamine elicits neuroprotection by inhibiting iNOS, NADPH oxidase and ROS in hippocampal slices stressed with anoxia/reoxygenation
Neuropharmacology, Vol. 62, Núm. 2, pp. 1082-1090
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Guanosine protects human neuroblastoma SH-SY5Y cells against mitochondrial oxidative stress by inducing heme oxigenase-1 via PI3K/Akt/GSK-3β pathway
Neurochemistry International, Vol. 61, Núm. 3, pp. 397-404
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Involvement of PI3K, GSK-3β and PPARγ in the antidepressant-like effect of folic acid in the forced swimming test in mice
Journal of Psychopharmacology, Vol. 26, Núm. 5, pp. 714-723
2011
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Cholinergic and neuroprotective drugs for the treatment of Alzheimer and neuronal vascular diseases. II. Synthesis, biological assessment, and molecular modelling of new tacrine analogues from highly substituted 2-aminopyridine-3- carbonitriles
Bioorganic and Medicinal Chemistry, Vol. 19, Núm. 1, pp. 122-133
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Chondroitin sulfate reduces cell death of rat hippocampal slices subjected to oxygen and glucose deprivation by inhibiting p38, NFκB and iNOS
Neurochemistry International, Vol. 58, Núm. 6, pp. 676-683
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N-Acylaminophenothiazines: Neuroprotective agents displaying multifunctional activities for a potential treatment of Alzheimer's disease
European Journal of Medicinal Chemistry, Vol. 46, Núm. 6, pp. 2224-2235
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Neuroprotective effect of guanosine against glutamate-induced cell death in rat hippocampal slices is mediated by the phosphatidylinositol-3 kinase/Akt/ glycogen synthase kinase 3β pathway activation and inducible nitric oxide synthase inhibition
Journal of Neuroscience Research, Vol. 89, Núm. 9, pp. 1400-1408
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Neurotoxicity induced by dexamethasone in the human neuroblastoma SH-SY5Y cell line can be prevented by folic acid
Neuroscience, Vol. 190, pp. 346-353
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Neurotoxicity induced by okadaic acid in the human neuroblastoma SH-SY5Y line can be differentially prevented by α7 and β2* nicotinic stimulation
Toxicological Sciences, Vol. 123, Núm. 1, pp. 193-205