RAFAEL LEÓN MARTÍNEZ-rekin lankidetzan egindako argitalpenak (12)

2022

  1. Curcumin-piperlongumine hybrids with a multitarget profile elicit neuroprotection in in vitro models of oxidative stress and hyperphosphorylation

    Antioxidants, Vol. 11, Núm. 1

  2. Enantioselective Synthesis and Pharmacological Evaluation of Aza‐CGP37157–Lipoic Acid Hybrids for the Treatment of Alzheimer’s Disease

    Antioxidants, Vol. 11, Núm. 1

2021

  1. Bisavenathramide analogues as nrf2 inductors and neuroprotectors in in vitro models of oxidative stress and hyperphosphorylation

    Antioxidants, Vol. 10, Núm. 6

  2. Enhanced stability and bioactivity of natural anticancer topoisomerase i inhibitors through cyclodextrin complexation

    Pharmaceutics, Vol. 13, Núm. 10

2020

  1. Antioxidant, anti-inflammatory and neuroprotective profiles of novel 1,4-dihydropyridine derivatives for the treatment of alzheimer’s disease

    Antioxidants, Vol. 9, Núm. 8, pp. 1-20

  2. Aza-CGP37157-lipoic hybrids designed as novel Nrf2-inducers and antioxidants exert neuroprotection against oxidative stress and show neuroinflammation inhibitory properties

    Drug Development Research, Vol. 81, Núm. 3, pp. 283-294

  3. NRF2 Regulation Processes as a Source of Potential Drug Targets against Neurodegenerative Diseases

    Biomolecules, Vol. 10, Núm. 6

2017

  1. Addition to "ITH14001, a CGP37157-Nimodipine Hybrid Designed to Regulate Calcium Homeostasis and Oxidative Stress, Exerts Neuroprotection in Cerebral Ischemia"

    ACS chemical neuroscience, Vol. 8, Núm. 1, pp. 210

  2. Discovery of the first dual GSK3β inhibitor/Nrf2 inducer. A new multitarget therapeutic strategy for Alzheimer's disease

    Scientific Reports, Vol. 7

  3. ITH14001, a CGP37157-Nimodipine Hybrid Designed to Regulate Calcium Homeostasis and Oxidative Stress, Exerts Neuroprotection in Cerebral Ischemia

    ACS Chemical Neuroscience, Vol. 8, Núm. 1, pp. 67-81

2014

  1. New 5-unsubstituted dihydropyridines with improved CaV1.3 selectivity as potential neuroprotective agents against ischemic injury

    Journal of Medicinal Chemistry, Vol. 57, Núm. 10, pp. 4313-4323

2013

  1. Identification of 4,6-diaryl-1,4-dihydropyridines as a new class of neuroprotective agents

    MedChemComm, Vol. 4, Núm. 3, pp. 590-594