MANUEL R.
BENITO DE LAS HERAS
Profesor emérito
ÁNGELA MARÍA
MARTÍNEZ VALVERDE
Profesora asociada
Publications by the researcher in collaboration with ÁNGELA MARÍA MARTÍNEZ VALVERDE (53)
2019
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Brown adipose tissue-specific insulin receptor knockout shows diabetic phenotype without insulin resistance
The Journal of clinical investigation, Vol. 129, Núm. 1, pp. 437
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Erratum: Brown adipose tissue-specific insulin receptor knockout shows diabetic phenotype without insulin resistance (Journal of Clinical Investigation (2019) 129:1 (437) DOI: 10.1172/JCI126191)
Journal of Clinical Investigation
2008
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PTP1B deficiency increases glucose uptake in neonatal hepatocytes: Involvement of IRA/GLUT2 complexes
American Journal of Physiology - Gastrointestinal and Liver Physiology, Vol. 295, Núm. 2
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Role of insulin receptor and balance in insulin receptor isoforms A and B in regulation of apoptosis in simian virus 40-immortalized neonatal hepatocytes
Molecular Biology of the Cell, Vol. 19, Núm. 3, pp. 1185-1198
2007
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Developmental switch from prolonged insulin action to increased insulin sensitivity in protein tyrosine phosphatase 1B-deficient hepatocytes
Endocrinology, Vol. 148, Núm. 2, pp. 594-608
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IRS-3 mediates insulin-induced glucose uptake in differentiated IRS-2-/- brown adipocytes
Molecular and Cellular Endocrinology, Vol. 268, Núm. 1-2, pp. 1-9
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Levels of protein tyrosine phosphatase 1B determine susceptibility to apoptosis in serum-deprived hepatocytes
Journal of Cellular Physiology, Vol. 212, Núm. 1, pp. 76-88
2006
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Differential mitogenic signaling in insulin receptor-deficient fetal pancreatic β-cells
Endocrinology, Vol. 147, Núm. 4, pp. 1959-1968
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Role of insulin receptor in the regulation of glucose uptake in neonatal hepatocytes
Endocrinology, Vol. 147, Núm. 8, pp. 3709-3718
2005
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Cellular Models for the Study of Type 2 Diabetes
The Metabolic Syndrome at the Beginning of the XXI Century: A Genetic and Molecular Approach (Elsevier Inc.), pp. 43-65
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The brown adipose cell: A model for understanding the molecular mechanisms of insulin resistance
Acta Physiologica Scandinavica, Vol. 183, Núm. 1, pp. 59-73
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The brown adipose cell: A unique model for understanding the molecular mechanism of insulin resistance
Mini-Reviews in Medicinal Chemistry, Vol. 5, Núm. 3, pp. 269-278
2004
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IRS-2 mediates the antiapoptotic effect of insulin in neonatal hepatocytes
Hepatology, Vol. 40, Núm. 6, pp. 1285-1294
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Susceptibility to apoptosis in insulin-like growth factor-I receptor-deficient brown adipocytes
Molecular Biology of the Cell, Vol. 15, Núm. 11, pp. 5101-5117
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Transforming growth factor-beta activates both pro-apoptotic and survival signals in fetal rat hepatocytes
Experimental Cell Research, Vol. 292, Núm. 1, pp. 209-218
2003
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Essential role of insulin-like growth factor I receptor in insulin-induced fetal brown adipocyte differentiation
Endocrinology, Vol. 144, Núm. 2, pp. 581-593
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Essential role of protein kinase Cζ in the impairment of insulin-induced glucose transport in IRS-2-deficient brown adipocytes
FEBS Letters, Vol. 536, Núm. 1-3, pp. 161-166
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Insulin-induced up-regulated uncoupling protein-1 expression is mediated by insulin receptor substrate 1 through the phosphatidylinositol 3-kinase/Akt signaling pathway in fetal brown adipocytes
Journal of Biological Chemistry, Vol. 278, Núm. 12, pp. 10221-10231
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Molecular mechanisms of insulin resistance in IRS-2-deficient hepatocytes
Diabetes, Vol. 52, Núm. 9, pp. 2239-2248
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Role of IRS-3 in the Insulin Signaling of IRS-1-deficient Brown Adipocytes
Journal of Biological Chemistry, Vol. 278, Núm. 46, pp. 45189-45199