Publicaciones en colaboración con investigadores/as de Harvard Medical School (14)

2018

  1. Male brown fat–Specific double knockout of IGFIR/IR: Atrophy, mitochondrial fission failure, impaired thermogenesis, and obesity

    Endocrinology, Vol. 159, Núm. 1, pp. 323-340

2016

  1. Essential role of IGFIR in the onset of male brown fat thermogenic function: Regulation of glucose homeostasis by differential organ-specific insulin sensitivity

    Endocrinology, Vol. 157, Núm. 4, pp. 1495-1511

2009

  1. β-cell hyperplasia induced by hepatic insulin resistance: Role of a liver-pancreas endocrine axis through insulin receptor A isoform

    Diabetes, Vol. 58, Núm. 4, pp. 820-828

2004

  1. IRS-2 mediates the antiapoptotic effect of insulin in neonatal hepatocytes

    Hepatology, Vol. 40, Núm. 6, pp. 1285-1294

2003

  1. Essential role of protein kinase Cζ in the impairment of insulin-induced glucose transport in IRS-2-deficient brown adipocytes

    FEBS Letters, Vol. 536, Núm. 1-3, pp. 161-166

  2. Insulin-induced up-regulated uncoupling protein-1 expression is mediated by insulin receptor substrate 1 through the phosphatidylinositol 3-kinase/Akt signaling pathway in fetal brown adipocytes

    Journal of Biological Chemistry, Vol. 278, Núm. 12, pp. 10221-10231

  3. Molecular mechanisms of insulin resistance in IRS-2-deficient hepatocytes

    Diabetes, Vol. 52, Núm. 9, pp. 2239-2248

2002

  1. Atypical β-adrenergic effects on insulin signaling and action in β 3-adrenoceptor-deficient brown adipocytes

    American Journal of Physiology - Endocrinology and Metabolism, Vol. 283, Núm. 1 46-1

  2. Increased insulin sensitivity in IGF-I receptor-deficient brown adipocytes

    Diabetes, Vol. 51, Núm. 3, pp. 743-754

  3. Novel adipocyte lines from brown fat: A model system for the study of differentiation, energy metabolism, and insulin action

    BioEssays, Vol. 24, Núm. 4, pp. 382-388

2001

  1. Essential role of insulin receptor substrate 1 in differentiation of brown adipocytes

    Molecular and Cellular Biology, Vol. 21, Núm. 1, pp. 319-329

2000

  1. Insulin and the β3-adrenoceptor differentially regulate uncoupling protein-1 expression

    Molecular Endocrinology, Vol. 14, Núm. 6, pp. 764-773

1999

  1. Insulin signaling in insulin receptor substrate (IRS)-1-deficient brown adipocytes: Requirement of IRS-1 for lipid synthesis

    Diabetes, Vol. 48, Núm. 11, pp. 2122-2131

  2. β3-Adrenergic stimulation differentially inhibits insulin signaling and decreases insulin-induced glucose uptake in brown adipocytes

    Journal of Biological Chemistry, Vol. 274, Núm. 49, pp. 34795-34802