MARÍA ISABEL
RODRÍGUEZ ESCUDERO
Profesora titular de universidad
Publicaciones (29) Publicaciones de MARÍA ISABEL RODRÍGUEZ ESCUDERO
2023
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A trans-kingdom T6SS effector induces the fragmentation of the mitochondrial network and activates innate immune receptor NLRX1 to promote infection
Nature Communications, Vol. 14, Núm. 1
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Functional analysis of PTEN variants of unknown significance from PHTS patients unveils complex patterns of PTEN biological activity in disease
European Journal of Human Genetics, Vol. 31, Núm. 5, pp. 568-577
2021
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A global analysis of the reconstitution of PTEN function by translational readthrough of PTEN pathogenic premature termination codons
Human Mutation, Vol. 42, Núm. 5, pp. 551-566
2020
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Klebsiella pneumoniae type VI secretion system-mediated microbial competition is PhoPQ controlled and reactive oxygen species dependent
PLoS Pathogens, Vol. 16, Núm. 3
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Modeling human disease in yeast: recreating the PI3K-PTEN-Akt signaling pathway in Saccharomyces cerevisiae
International microbiology: official journal of the Spanish Society for Microbiology, Vol. 23, Núm. 1, pp. 75-87
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The TIR-domain containing effectors BtpA and BtpB from Brucella abortus impact NAD metabolism
PLoS Pathogens, Vol. 16, Núm. 4
2019
2018
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A pathogenic role for germline PTEN variants which accumulate into the nucleus
European Journal of Human Genetics, Vol. 26, Núm. 8, pp. 1180-1187
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Heterologous mammalian Akt disrupts plasma membrane homeostasis by taking over TORC2 signaling in Saccharomyces cerevisiae
Scientific Reports, Vol. 8, Núm. 1
2017
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Insights into the pathological mechanisms of p85α mutations using a yeast-based phosphatidylinositol 3-kinase model
Bioscience Reports, Vol. 37, Núm. 2
2016
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Studying Coxiella burnetii type IV substrates in the yeast saccharomyces cerevisiae: Focus on subcellular localization and protein aggregation
PLoS ONE, Vol. 11, Núm. 1
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The Salmonella effector SteA binds phosphatidylinositol 4-phosphate for subcellular targeting within host cells
Cellular Microbiology, Vol. 18, Núm. 7, pp. 949-969
2015
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A functional dissection of PTEN N-terminus: Implications in PTEN subcellular targeting and tumor suppressor activity
PLoS ONE, Vol. 10, Núm. 4
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Caracterización del efector translocado de "Salmonella" Typhimurium SteA en el modelo heterólogo de levadura
Avances en microbiología
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The yeast cell wall integrity pathway signals from recycling endosomes upon elimination of phosphatidylinositol (4,5)-bisphosphate by mammalian phosphatidylinositol 3-kinase
Cellular Signalling, Vol. 27, Núm. 11, pp. 2272-2284
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Yeast-based methods to assess PTEN phosphoinositide phosphatase activity in vivo
Methods, Vol. 77, pp. 172-179
2012
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A yeast-based in vivo bioassay to screen for class i phosphatidylinositol 3-kinase specific inhibitors
Journal of Biomolecular Screening, Vol. 17, Núm. 8, pp. 1018-1029
2011
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A comprehensive functional analysis of PTEN mutations: Implications in tumor- and autism-related syndromes
Human Molecular Genetics, Vol. 20, Núm. 21, pp. 4132-4142
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Interaction of the Salmonella Typhimurium effector protein SopB with host cell Cdc42 is involved in intracellular replication
Molecular Microbiology, Vol. 80, Núm. 5, pp. 1220-1240
2009
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Addressing the effects of Salmonella internalization in host cell signaling on a reverse-phase protein array
Proteomics, Vol. 9, Núm. 14, pp. 3652-3665