CARLOS
GUILLÉN VIEJO
Profesor titular de universidad
MANUEL R.
BENITO DE LAS HERAS
Profesor emérito
Publicaciones en las que colabora con MANUEL R. BENITO DE LAS HERAS (24)
2024
2021
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Biological actions and molecular mechanisms of sambucus Nigra L. In neurodegeneration: A cell culture approach
Molecules, Vol. 26, Núm. 16
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Dietary polyphenols in metabolic and neurodegenerative diseases: Molecular targets in autophagy and biological effects
Antioxidants, Vol. 10, Núm. 2, pp. 1-22
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Human amylin aggregates release within exosomes as a protective mechanism in pancreatic β cells: Pancreatic β-hippocampal cell communication
Biochimica et Biophysica Acta - Molecular Cell Research, Vol. 1868, Núm. 5
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Insulin Resistance and Diabetes Mellitus in Alzheimer's Disease
Cells, Vol. 10, Núm. 5
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Sirtuins in mechanistic target of rapamycin complex 1 signaling
Sirtuin Biology in Medicine: Targeting New Avenues of Care in Development, Aging, and Disease (Elsevier), pp. 191-212
2019
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Essential role of glucokinase in the protection of pancreatic β cells to the glucose energetic status
Cell Death Discovery, Vol. 5, Núm. 1
2018
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MTORC1 overactivation as a key aging factor in the progression to type 2 diabetes mellitus
Frontiers in Endocrinology, Vol. 9, Núm. OCT
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Male brown fat–Specific double knockout of IGFIR/IR: Atrophy, mitochondrial fission failure, impaired thermogenesis, and obesity
Endocrinology, Vol. 159, Núm. 1, pp. 323-340
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Pancreatic β cells overexpressing hIAPP impaired mitophagy and unbalanced mitochondrial dynamics
Cell Death and Disease, Vol. 9, Núm. 5
2017
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MTORC1 regulates both general autophagy and mitophagy induction after oxidative phosphorylation uncoupling
Molecular and Cellular Biology, Vol. 37, Núm. 23
2016
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Essential role of IGFIR in the onset of male brown fat thermogenic function: Regulation of glucose homeostasis by differential organ-specific insulin sensitivity
Endocrinology, Vol. 157, Núm. 4, pp. 1495-1511
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La proteína tuberina: diana terapéutica para activar autofagia y mitofagia evitando la progresión a la diabetes tipo 2
Anales de la Real Academia Nacional de Farmacia, Vol. 82, Núm. 4, pp. 424-442
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TSC2 N-terminal lysine acetylation status affects to its stability modulating mTORC1 signaling and autophagy
Biochimica et Biophysica Acta - Molecular Cell Research, Vol. 1863, Núm. 11, pp. 2658-2667
2014
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Antagonistic effect of TNF-alpha and insulin on uncoupling protein 2 (UCP-2) expression and vascular damage
Cardiovascular Diabetology, Vol. 13, Núm. 1
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Pancreatic b-Cell failure mediated by mTORC1 hyperactivity and autophagic impairment
Diabetes, Vol. 63, Núm. 9, pp. 2996-3008
2013
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Autophagy impairment aggravates the inhibitory effects of high glucose on osteoblast viability and function
Biochemical Journal, Vol. 455, Núm. 3, pp. 329-337
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Concerted expression of the thermogenic and bioenergetic mitochondrial protein machinery in brown adipose tissue
Journal of Cellular Biochemistry, Vol. 114, Núm. 10, pp. 2306-2313
2012
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Autophagy plays a protective role in endoplasmic reticulum stress-mediated pancreatic β cell death
Autophagy, Vol. 8, Núm. 12, pp. 1757-1768
2010
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Role of the TSC1-TSC2 complex in the integration of insulin and glucose signaling involved in pancreatic β-cell proliferation
Endocrinology, Vol. 151, Núm. 7, pp. 3084-3094