Publicaciones en colaboración con investigadores/as de Instituto de Salud Carlos III (15)

2022

  1. Dehydroisohispanolone as a Promising NLRP3 Inhibitor Agent: Bioevaluation and Molecular Docking

    Pharmaceuticals, Vol. 15, Núm. 7

2020

  1. Current status of terpenoids as inflammasome inhibitors

    Biochemical Pharmacology, Vol. 172

  2. Dehydrohispanolone Derivatives Attenuate the Inflammatory Response through the Modulation of Inflammasome Activation

    Journal of Natural Products, Vol. 83, Núm. 7, pp. 2155-2164

2019

  1. Amphiphilic acrylic nanoparticles containing the poloxamer star Bayfit®10WF15 as ophthalmic drug carriers

    Polymers, Vol. 11, Núm. 7

  2. α-hispanolol induces apoptosis and suppresses migration and invasion of glioblastoma cells likely via downregulation of MMP-2/9 expression and p38MAPK attenuation

    Frontiers in Pharmacology, Vol. 10, Núm. JULY

2018

  1. A hispanolone-derived diterpenoid inhibits M2-Macrophage polarization in vitro via JAK/STAT and attenuates chitin induced inflammation in vivo

    Biochemical Pharmacology, Vol. 154, pp. 373-383

  2. Semisynthesis and inhibitory effects of solidagenone derivatives on TLR-mediated inflammatory responses

    Molecules, Vol. 23, Núm. 12

2016

  1. 8,9-Dehydrohispanolone-15,16-lactol diterpene prevents LPS-triggered inflammatory responses by inhibiting endothelial activation

    Biochemical Journal, Vol. 473, Núm. 14, pp. 2061-2071

  2. Novel water-soluble mucoadhesive carbosilane dendrimers for ocular administration

    Molecular Pharmaceutics, Vol. 13, Núm. 9, pp. 2966-2976

2015

  1. Anti-inflammatory activity and phenolic profile of propolis from two locations in Región Metropolitana de Santiago, Chile

    Journal of Ethnopharmacology, Vol. 168, pp. 37-44

  2. Biological evaluation of angular disubstituted naphthoimidazoles as anti-inflammatory agents

    Bioorganic and Medicinal Chemistry Letters, Vol. 25, Núm. 19, pp. 4210-4213

  3. Novel biodegradable polyesteramide microspheres for controlled drug delivery in Ophthalmology

    Journal of Controlled Release, Vol. 211, pp. 105-117

  4. α-Hispanolol sensitizes hepatocellular carcinoma cells to TRAIL-induced apoptosis via death receptor up-regulation

    Toxicology and Applied Pharmacology, Vol. 286, Núm. 3, pp. 168-177

2014

  1. Design and characterization of an ocular topical liposomal preparation to replenish the lipids of the tear film

    Investigative Ophthalmology and Visual Science, Vol. 55, Núm. 12, pp. 7839-7847

2013

  1. Critical role of the death receptor pathway in the antitumoral effects induced by hispanolone derivatives

    Oncogene, Vol. 32, Núm. 2, pp. 259-268