Publicaciones en colaboración con investigadores/as de Centro de Investigaciones Biológicas (27)

2022

  1. Factor H-Related Protein 1 Drives Disease Susceptibility and Prognosis in C3 Glomerulopathy

    Journal of the American Society of Nephrology : JASN, Vol. 33, Núm. 6, pp. 1137-1153

2018

  1. Complete functional characterization of disease-associated genetic variants in the complement factor H gene

    Kidney International, Vol. 93, Núm. 2, pp. 470-481

  2. Factor H competitor generated by gene conversion events associates with atypical hemolytic uremic syndrome

    Journal of the American Society of Nephrology, Vol. 29, Núm. 1, pp. 240-249

  3. How novel structures inform understanding of complement function

    Seminars in Immunopathology, Vol. 40, Núm. 1, pp. 3-14

2017

  1. Elevated factor H–related protein 1 and factor H pathogenic variants decrease complement regulation in IgA nephropathy

    Kidney International, Vol. 92, Núm. 4, pp. 953-963

  2. FHR-1 binds to C-reactive protein and enhances rather than inhibits complement activation

    Journal of Immunology, Vol. 199, Núm. 1, pp. 292-303

  3. Functional and structural characterization of four mouse monoclonal antibodies to complement C3 with potential therapeutic and diagnostic applications

    European Journal of Immunology, Vol. 47, Núm. 3, pp. 504-515

  4. Interaction between multimeric von willebrand factor and complement: A fresh look to the pathophysiology of microvascular thrombosis

    Journal of Immunology, Vol. 199, Núm. 3, pp. 1021-1040

2016

  1. Familial C3 glomerulonephritis caused by a novel CFHR5-CFHR2 fusion gene

    Molecular Immunology, Vol. 77, pp. 89-96

  2. Molecular basis of factor H R1210C association with ocular and renal diseases

    Journal of the American Society of Nephrology, Vol. 27, Núm. 5, pp. 1305-1311

  3. Serum properdin consumption as a biomarker of C5 convertase dysregulation in C3 glomerulopathy

    Clinical and Experimental Immunology, Vol. 184, Núm. 1, pp. 118-125

2015

  1. A novel atypical hemolytic uremic syndrome-associated hybrid CFHR1/CFH gene encoding a fusion protein that antagonizes factor H-dependent complement regulation

    Journal of the American Society of Nephrology, Vol. 26, Núm. 1, pp. 209-219

  2. Factor H-related proteins determine complement-activating surfaces

    Trends in Immunology, Vol. 36, Núm. 6, pp. 374-384

  3. The molecular and structural bases for the association of complement C3 mutations with atypical hemolytic uremic syndrome

    Molecular Immunology, Vol. 66, Núm. 2, pp. 263-273

2014

  1. A novel antibody against human factor B that blocks formation of the C3bB proconvertase and inhibits complement activation in disease models

    Journal of Immunology, Vol. 193, Núm. 11, pp. 5567-5575

  2. Genetics of atypical hemolytic uremic syndrome (aHUS)

    Seminars in Thrombosis and Hemostasis, Vol. 40, Núm. 4, pp. 422-430

2013

  1. C3 glomerulopathy-associated CFHR1 mutation alters FHR oligomerization and complement regulation

    Journal of Clinical Investigation, Vol. 123, Núm. 6, pp. 2434-2446

  2. Structural basis for the stabilization of the complement alternative pathway C3 convertase by properdin

    Proceedings of the National Academy of Sciences of the United States of America, Vol. 110, Núm. 33, pp. 13504-13509

2012

  1. Atypical hemolytic uremic syndrome-associated variants and autoantibodies impair binding of factor H and factor H-related protein 1 to pentraxin 3

    Journal of Immunology, Vol. 189, Núm. 4, pp. 1858-1867

  2. Complement dysregulation and disease: From genes and proteins to diagnostics and drugs

    Immunobiology, Vol. 217, Núm. 11, pp. 1034-1046