MARÍA ISABEL
COLADO MEGÍAS
Catedrática de universidad
AstraZeneca (United Kingdom)
Cambridge, Reino UnidoPublications en collaboration avec des chercheurs de AstraZeneca (United Kingdom) (20)
2006
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The acute and long-term neurotoxic effects of MDMA on marble burying behaviour in mice
Journal of Psychopharmacology, Vol. 20, Núm. 2, pp. 264-271
2005
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Studies on the effect of MDMA ('ecstasy') on the body temperature of rats housed at different ambient room temperatures
British Journal of Pharmacology, Vol. 146, Núm. 2, pp. 306-312
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The role of 5-HT in the impairment of thermoregulation observed in rats administered MDMA ('ecstasy') when housed at high ambient temperature
Psychopharmacology, Vol. 179, Núm. 4, pp. 884-890
2004
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A review of the mechanisms involved in the acute MDMA (ecstasy)-induced hyperthermic response
European Journal of Pharmacology, Vol. 500, Núm. 1-3 SPEC. ISS., pp. 3-13
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Acute and long-term of MDMA on cerebral dopamine biochemistry and function
Psychopharmacology, Vol. 173, Núm. 3-4, pp. 249-263
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Effect of ambient temperature and a prior neurotoxic dose of 3,4-methylenedioxymethamphetamine (MDMA) on the hyperthermic responce of rats to a single or ('binge' ingestion) low of MDMA
Psychopharmacology, Vol. 173, Núm. 3-4, pp. 264-269
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Effect of repeated ('binge') dosing of MDMA to rats housed at normal and high temperature on neurotoxic damage to cerebral 5-HT and dopamine neurones
Journal of Psychopharmacology, Vol. 18, Núm. 3, pp. 412-416
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Hyperthermic and neurotoxic effect of 3,4-methylenedioxymethamphetamine (MDMA) in guinea pigs
Psychopharmacology
2003
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The pharmacology and clinical pharmacology of 3,4-methylenedioxymethamphetamine (MDMA, "ecstasy")
Pharmacological Reviews, Vol. 55, Núm. 3, pp. 463-508
2001
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Studies on the neuroprotective effect of the enantiomers of AR-A008055, a compound structurally related to clomethiazole, on MDMA ("ecstasy")-inducedneurodegeneration in rat brain
Psychopharmacology, Vol. 157, Núm. 1, pp. 82-88
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The mechanisms involved in the long-lasting neuroprotective effect of fluoxetine against MDMA ('ecstasy')-induced degeneration of 5-HT nerve endings in rat brain
British Journal of Pharmacology, Vol. 134, Núm. 1, pp. 46-57
1997
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A study of the neurotoxic effect of MDMA ('ecstasy') on 5-HT neurones in the brains of mothers and neonates following administration of the drug during pregnancy
British Journal of Pharmacology, Vol. 121, Núm. 4, pp. 827-833
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In vivo evidence for free radical involvement in the degeneration of rat brain 5-HT following administration of MDMA ('ecstasy') and p-chloroamphetamine but not the degeneration following fenfluramine
British Journal of Pharmacology, Vol. 121, Núm. 5, pp. 889-900
1996
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The spin trap reagent PBN attenuates degeneration of 5-HT neurones in rat brain induced by p-chloroamphetamine but not fenfluramine
Neuropharmacology, Vol. 35, Núm. 11, pp. 1615-1620
1995
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The hyperthermic and neurotoxic effects of ‘Ecstasy’ (MDMA) and 3,4 methylenedioxyamphetamine (MDA) in the Dark Agouti (DA) rat, a model of the CYP2D6 poor metabolizer phenotype
British Journal of Pharmacology, Vol. 115, Núm. 7, pp. 1281-1289
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The spin trap reagent α-phenyl-N-tert-butylnitrone prevents 'ecstasy'-induced neurodegeneration of 5-hydroxytryptamine neurones
European Journal of Pharmacology, Vol. 280, Núm. 3, pp. 343-346
1994
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A study of the mechanism of MDMA (‘Ecstasy’)‐induced neurotoxicity of 5‐HT neurones using chlormethiazole, dizocilpine and other protective compounds
British Journal of Pharmacology, Vol. 111, Núm. 1, pp. 131-136
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Chlormethiazole and Dizocilpine Block the Behavioural, but Not the Neurotoxic Effects of 5,7‐Dihydroxytryptamine in Mice
Pharmacology & Toxicology, Vol. 74, Núm. 1, pp. 40-42
1993
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5‐HT loss in rat brain following 3, 4‐methylenedioxymethamphetamine (MDMA), p‐chloroamphetamine and fenfluramine administration and effects of chlormethiazole and dizocilpine
British Journal of Pharmacology, Vol. 108, Núm. 3, pp. 583-589
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Striatal dopamine release in vivo following neurotoxic doses of methamphetamine and effect of the neuroprotective drugs, chlormethiazole and dizocilpine
British Journal of Pharmacology, Vol. 108, Núm. 3, pp. 590-596