JOSÉ ÁNGEL
MORALES GARCÍA
Profesor titular de universidad
Centro de Investigaciones Biológicas
Madrid, EspañaPublicaciones en colaboración con investigadores/as de Centro de Investigaciones Biológicas (8)
2017
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Biological and Pharmacological Characterization of Benzothiazole-Based CK-1δ Inhibitors in Models of Parkinson's Disease
ACS Omega, Vol. 2, Núm. 8, pp. 5215-5220
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Pharmacological tools based on imidazole scaffold proved the utility of PDE10A inhibitors for Parkinson's disease
Future Medicinal Chemistry, Vol. 9, Núm. 8, pp. 731-748
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Phosphodiesterase7 Inhibition Activates Adult Neurogenesis in Hippocampus and Subventricular Zone In Vitro and In Vivo
Stem Cells, Vol. 35, Núm. 2, pp. 458-472
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Subtly Modulating Glycogen Synthase Kinase 3 β: Allosteric Inhibitor Development and Their Potential for the Treatment of Chronic Diseases
Journal of Medicinal Chemistry, Vol. 60, Núm. 12, pp. 4983-5001
2015
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PDE7 inhibitor TC3.6 ameliorates symptomatology in a model of primary progressive multiple sclerosis
British Journal of Pharmacology, Vol. 172, Núm. 17, pp. 4277-4290
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Phosphodiesterase 7 inhibition induces dopaminergic neurogenesis in hemiparkinsonian rats
Stem Cells Translational Medicine, Vol. 4, Núm. 6, pp. 564-575
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Silencing phosphodiesterase 7B gene by lentiviral-shRNA interference attenuates neurodegeneration and motor deficits in hemiparkinsonian mice
Neurobiology of Aging, Vol. 36, Núm. 2, pp. 1160-1173
2014
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Modulation of cAMP-specific PDE without emetogenic activity: New sulfide-like PDE7 inhibitors
Journal of Medicinal Chemistry, Vol. 57, Núm. 20, pp. 8590-8607