JOSÉ ÁNGEL
MORALES GARCÍA
Profesor titular de universidad
Instituto de Investigaciones Biomédicas Alberto Sols
Madrid, EspañaPublications in collaboration with researchers from Instituto de Investigaciones Biomédicas Alberto Sols (41)
2024
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Discovery of a potent melatonin-based inhibitor of quinone reductase-2 with neuroprotective and neurogenic properties
European Journal of Medicinal Chemistry, Vol. 277
2023
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C/EBPβ Regulates TFAM Expression, Mitochondrial Function and Autophagy in Cellular Models of Parkinson’s Disease
International Journal of Molecular Sciences, Vol. 24, Núm. 2
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Changes in Liver Lipidomic Profile in G2019S-LRRK2 Mouse Model of Parkinson’s Disease
Cells, Vol. 12, Núm. 5
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Neuroprotective properties of queen bee acid by autophagy induction
Cell Biology and Toxicology, Vol. 39, Núm. 3, pp. 751-770
2022
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Neuroprotective and Anti-Inflammatory Effects of Linoleic Acid in Models of Parkinson’s Disease: The Implication of Lipid Droplets and Lipophagy
Cells, Vol. 11, Núm. 15
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Resveratrol-Based MTDLs to Stimulate Defensive and Regenerative Pathways and Block Early Events in Neurodegenerative Cascades
Journal of Medicinal Chemistry, Vol. 65, Núm. 6, pp. 4727-4751
2021
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The immune system through the lens of alcohol intake and gut microbiota
International Journal of Molecular Sciences, Vol. 22, Núm. 14
2020
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Metabolic alterations in plasma from patients with familial and idiopathic Parkinson's disease
Aging, Vol. 12, Núm. 17, pp. 16690-16708
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Phosphodiesterase 7 Regulation in Cellular and Rodent Models of Parkinson’s Disease
Molecular Neurobiology, Vol. 57, Núm. 2, pp. 806-822
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Tuning melatonin receptor subtype selectivity in oxadiazolone-based analogues: Discovery of QR2 ligands and NRF2 activators with neurogenic properties
European Journal of Medicinal Chemistry, Vol. 190
2019
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New flavonoid–N,N-dibenzyl(N-methyl)amine hybrids: Multi-target-directed agents for Alzheimer´s disease endowed with neurogenic properties
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol. 34, Núm. 1, pp. 712-727
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Novel approaches for the treatment of alzheimer’s and parkinson’s disease
International Journal of Molecular Sciences, Vol. 20, Núm. 3
2018
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Neurogenic and neuroprotective donepezil-flavonoid hybrids with sigma-1 affinity and inhibition of key enzymes in Alzheimer's disease
European Journal of Medicinal Chemistry, Vol. 156, pp. 534-553
2017
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Biological and Pharmacological Characterization of Benzothiazole-Based CK-1δ Inhibitors in Models of Parkinson's Disease
ACS Omega, Vol. 2, Núm. 8, pp. 5215-5220
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CCAAT/Enhancer binding protein β silencing mitigates glial activation and neurodegeneration in a rat model of Parkinson's disease
Scientific Reports, Vol. 7, Núm. 1
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Pharmacological tools based on imidazole scaffold proved the utility of PDE10A inhibitors for Parkinson's disease
Future Medicinal Chemistry, Vol. 9, Núm. 8, pp. 731-748
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Phosphodiesterase7 Inhibition Activates Adult Neurogenesis in Hippocampus and Subventricular Zone In Vitro and In Vivo
Stem Cells, Vol. 35, Núm. 2, pp. 458-472
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Subtly Modulating Glycogen Synthase Kinase 3 β: Allosteric Inhibitor Development and Their Potential for the Treatment of Chronic Diseases
Journal of Medicinal Chemistry, Vol. 60, Núm. 12, pp. 4983-5001
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The alkaloids of Banisteriopsis caapi, the plant source of the Amazonian hallucinogen Ayahuasca, stimulate adult neurogenesis in vitro
Scientific Reports, Vol. 7, Núm. 1
2016
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Complement component 3 (C3) expression in the hippocampus after excitotoxic injury: Role of C/EBPβ
Journal of Neuroinflammation, Vol. 13, Núm. 1