Publikationen in Zusammenarbeit mit Forschern von Centro Nacional de Investigaciones Oncológicas (53)

2022

  1. A mouse model for Li-Fraumeni-Like Syndrome with cardiac angiosarcomas associated to POT1 mutations

    PLoS Genetics, Vol. 18, Núm. 6

  2. Consequences of telomere dysfunction in fibroblasts, club and basal cells for lung fibrosis development

    Nature Communications, Vol. 13, Núm. 1

2020

  1. The mTOR pathway is necessary for survival of mice with short telomeres

    Nature Communications, Vol. 11, Núm. 1

2019

  1. Safety of Whole-Body Abrogation of the TRF1 Shelterin Protein in Wild-Type and Cancer-Prone Mouse Models

    iScience, Vol. 19, pp. 572-585

2018

  1. Therapeutic effects of telomerase in mice with pulmonary fibrosis induced by damage to the lungs and short telomeres

    eLife, Vol. 7

2016

  1. A genetic interaction between RAP1 and telomerase reveals an unanticipated role for RAP1 in telomere maintenance

    Aging Cell, Vol. 15, Núm. 6, pp. 1113-1125

  2. G6PD protects from oxidative damage and improves healthspan in mice

    Nature Communications, Vol. 7

2015

  1. Loss of Tribbles pseudokinase-3 promotes Akt-driven tumorigenesis via FOXO inactivation

    Cell Death and Differentiation, Vol. 22, Núm. 1, pp. 131-144

  2. Mice with Pulmonary Fibrosis Driven by Telomere Dysfunction

    Cell Reports, Vol. 12, Núm. 2, pp. 286-299

  3. Role of cannabinoid receptor CB<inf>2</inf> in HER2 pro-oncogenic signaling in breast cancer

    Journal of the National Cancer Institute, Vol. 107, Núm. 6

  4. TRIB3 suppresses tumorigenesis by controlling mTORC2/AKT/FOXO signaling

    Molecular and Cellular Oncology, Vol. 2, Núm. 3

  5. Therapeutic inhibition of TRF1 impairs the growth of p53-deficient K-RasG12V-induced lung cancer by induction of telomeric DNA damage

    EMBO Molecular Medicine, Vol. 7, Núm. 7, pp. 930-949

2014

  1. Essential role for the TRF2 telomere protein in adult skin homeostasis

    Aging Cell, Vol. 13, Núm. 4, pp. 656-668

  2. In vivo role of checkpoint kinase 2 in signaling telomere dysfunction

    Aging Cell, Vol. 13, Núm. 5, pp. 810-816

  3. Increased melanoma formation and dissemination in TyrNRas mice deficient in the tumor suppressor Ing1

    Pigment Cell and Melanoma Research, Vol. 27, Núm. 4, pp. 674-677

  4. Sox4 Links Tumor Suppression to Accelerated Aging in Mice by Modulating Stem Cell Activation

    Cell Reports, Vol. 8, Núm. 2, pp. 487-500

2013

  1. Lkb1 Loss Promotes Tumor Progression of BRAFV600E-Induced Lung Adenomas

    PLoS ONE, Vol. 8, Núm. 6

  2. RAP1 Protects from Obesity through Its Extratelomeric Role Regulating Gene Expression

    Cell Reports, Vol. 3, Núm. 6, pp. 2059-2074

  3. Telomerase Reverse Transcriptase Synergizes with Calorie Restriction to Increase Health Span and Extend Mouse Longevity

    PLoS ONE, Vol. 8, Núm. 1

2012

  1. 53BP1 deficiency combined with telomere dysfunction activates ATR-dependent DNA damage response

    Journal of Cell Biology, Vol. 197, Núm. 2, pp. 283-300