MIGUEL
DÍAZ HERNÁNDEZ
Profesor titular de universidad
Centro de Biología Molecular Severo Ochoa
Madrid, EspañaPublicaciones en colaboración con investigadores/as de Centro de Biología Molecular Severo Ochoa (18)
2019
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Peripheral nervous system effects in the PS19 tau transgenic mouse model of tauopathy
Neuroscience Letters, Vol. 698, pp. 204-208
2018
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The regulation of proteostasis in glial cells by nucleotide receptors is key in acute neuroinflammation
FASEB Journal, Vol. 32, Núm. 6, pp. 3020-3032
2017
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Regulation of proteasome activity by P2Y2 receptor underlies the neuroprotective effects of extracellular nucleotides
Biochimica et Biophysica Acta - Molecular Basis of Disease, Vol. 1863, Núm. 1, pp. 43-51
2015
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TNAP plays a key role in neural differentiation as well as in neurodegenerative disorders
Sub-Cellular Biochemistry, Vol. 76, pp. 375-385
2014
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Sources of extracellular tau and its signaling
Journal of Alzheimer's Disease, Vol. 40, Núm. S1
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Tau triggers tear secretion by interacting with muscarinic acetylcholine receptors in New Zealand white rabbits
Journal of Alzheimer's Disease, Vol. 40, Núm. S1
2012
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In vivo P2X7 inhibition reduces amyloid plaques in Alzheimer's disease through GSK3β and secretases
Neurobiology of Aging, Vol. 33, Núm. 8, pp. 1816-1828
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Looking for novel functions of tau
Biochemical Society Transactions
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α-Synuclein accumulates in huntingtin inclusions but forms independent filaments and its deficiency attenuates early phenotype in a mouse model of Huntington's disease
Human Molecular Genetics, Vol. 21, Núm. 3, pp. 495-510
2009
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Altered P2X7-receptor level and function in mouse models of Huntington's disease and therapeutic efficacy of antagonist administration
FASEB Journal, Vol. 23, Núm. 6, pp. 1893-1906
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Ca2+/calmodulin-dependent kinase II signalling cascade mediates P2X7 receptor-dependent inhibition of neuritogenesis in neuroblastoma cells
FEBS Journal, Vol. 276, Núm. 18, pp. 5307-5325
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Characteristics and consequences of muscarinic receptor activation by tau protein
European Neuropsychopharmacology, Vol. 19, Núm. 10, pp. 708-717
2008
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Extracellular tau promotes intracellular calcium increase through M1 and M3 muscarinic receptors in neuronal cells
Molecular and Cellular Neuroscience, Vol. 37, Núm. 4, pp. 673-681
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Inhibition of the ATP-gated P2X7 receptor promotes axonal growth and branching in cultured hippocampal neurons
Journal of Cell Science, Vol. 121, Núm. 22, pp. 3717-3728
2007
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Is the ubiquitin-proteasome system impaired in Huntington's disease?
Cellular and Molecular Life Sciences, Vol. 64, Núm. 17, pp. 2245-2257
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Testing the possible inhibition of proteasome by direct interaction with ubiquitylated and aggregated huntingtin
Brain Research Bulletin, Vol. 72, Núm. 2-3 SPEC. ISS., pp. 121-123
2006
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Inhibition of 26S proteasome activity by huntingtin filaments but not inclusion bodies isolated from mouse and human brain
Journal of Neurochemistry, Vol. 98, Núm. 5, pp. 1585-1596
2004
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Testing the ubiquitin-proteasome hypothesis of neurodegeneration in vivo
Trends in Neurosciences