Publications en collaboration avec des chercheurs de Universidad Autónoma de Madrid (26)

2022

  1. TNAP upregulation is a critical factor in Tauopathies and its blockade ameliorates neurotoxicity and increases life-expectancy

    Neurobiology of Disease, Vol. 165

2019

  1. Amyloid peptide induced neuroinflammation increases the P2X7 receptor expression in microglial cells, impacting on its functionality

    Frontiers in Cellular Neuroscience, Vol. 13

2018

  1. Haploinsufficient TNAP mice display decreased extracellular ATP levels and expression of Pannexin-1 channels

    Frontiers in Pharmacology, Vol. 9, Núm. MAR

  2. MicroRNA-22 controls aberrant neurogenesis and changes in neuronal morphology after status epilepticus

    Frontiers in Molecular Neuroscience, Vol. 11

  3. The regulation of proteostasis in glial cells by nucleotide receptors is key in acute neuroinflammation

    FASEB Journal, Vol. 32, Núm. 6, pp. 3020-3032

2015

  1. Tissue-nonspecific Alkaline Phosphatase Regulates Purinergic Transmission in the Central Nervous System during Development and Disease

    Computational and Structural Biotechnology Journal, Vol. 13, pp. 95-100

2013

  1. P2X receptors as targets for the treatment of status epilepticus

    Frontiers in Cellular Neuroscience, Vol. 7, Núm. NOV

2012

  1. Adenylate cyclase 5 coordinates the action of ADP, P2Y1, P2Y13 and ATP-gated P2X7 receptors on axonal elongation

    Journal of Cell Science, Vol. 125, Núm. 1, pp. 176-188

  2. Tau overexpression results in its secretion via membrane vesicles

    Neurodegenerative Diseases, Vol. 10, Núm. 1-4, pp. 73-75

  3. α-Synuclein accumulates in huntingtin inclusions but forms independent filaments and its deficiency attenuates early phenotype in a mouse model of Huntington's disease

    Human Molecular Genetics, Vol. 21, Núm. 3, pp. 495-510

2011

  1. Loss of striatal type 1 cannabinoid receptors is a key pathogenic factor in Huntington's disease

    Brain, Vol. 134, Núm. 1, pp. 119-136

2010

  1. Acute polyglutamine expression in inducible mouse model unravels ubiquitin/proteasome system impairment and permanent recovery attributable to aggregate formation

    Journal of Neuroscience, Vol. 30, Núm. 10, pp. 3675-3688

  2. PH domain leucine-rich repeat protein phosphatase 1 contributes to maintain the activation of the PI3K/Akt pro-survival pathway in Huntington's disease striatum

    Cell Death and Differentiation, Vol. 17, Núm. 2, pp. 324-335

  3. Tissue-nonspecific alkaline phosphatase promotes the neurotoxicity effect of extracellular tau

    Journal of Biological Chemistry, Vol. 285, Núm. 42, pp. 32539-32548

2009

  1. Accumulation of ubiquitin conjugates in a polyglutamine disease model occurs without global ubiquitin/proteasome system impairment

    Proceedings of the National Academy of Sciences of the United States of America, Vol. 106, Núm. 33, pp. 13986-13991

  2. Reduced calcineurin protein levels and activity in exon-1 mouse models of Huntington's disease: Role in excitotoxicity

    Neurobiology of Disease, Vol. 36, Núm. 3, pp. 461-469

2007

  1. BH3-only proteins Bid and BimEL are differentially involved in neuronal dysfunction in mouse models of Huntington's disease

    Journal of Neuroscience Research

2006

  1. Extracellular tau is toxic to neuronal cells

    FEBS Letters, Vol. 580, Núm. 20, pp. 4842-4850

  2. Inhibition of 26S proteasome activity by huntingtin filaments but not inclusion bodies isolated from mouse and human brain

    Journal of Neurochemistry, Vol. 98, Núm. 5, pp. 1585-1596

  3. Reduced expression of the TrkB receptor in Huntington's disease mouse models and in human brain

    European Journal of Neuroscience, Vol. 23, Núm. 3, pp. 649-658