JOSÉ LUIS
MARCO CONTELLES
Investigador en el periodo 2018-2019
EVA
RAMOS ALONSO
Profesora titular de universidad
Publicaciones en las que colabora con EVA RAMOS ALONSO (18)
2022
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Synthesis and Pharmacological Evaluation of New N-Sulfonylureas as NLRP3 Inflammasome Inhibitors: Identification of a Hit Compound to Treat Gout
Journal of Medicinal Chemistry, Vol. 65, Núm. 8, pp. 6250-6260
2020
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Highlights of ASS234: A novel and promising therapeutic agent for Alzheimer's disease therapy
Neural Regeneration Research, Vol. 15, Núm. 1, pp. 30-35
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In Vitro and in Silico ADME-Tox Profiling and Safety Significance of Multifunctional Monoamine Oxidase Inhibitors Targeting Neurodegenerative Diseases
ACS Chemical Neuroscience, Vol. 11, Núm. 22, pp. 3793-3801
2019
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Quinoxalinetacrine QT78, a cholinesterase inhibitor as a potential ligand for Alzheimer’s disease therapy
Molecules, Vol. 24, Núm. 8
2018
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Analysis of gene expression profiles of CR80, a neuroprotective 1,8-Naphthyridine
Future Medicinal Chemistry, Vol. 10, Núm. 11, pp. 1289-1300
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In silico assessment of the metabolism and its safety significance of multitarget propargylamine ASS234
CNS Neuroscience and Therapeutics
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Modulation of Heat Shock Response Proteins by ASS234, Targeted for Neurodegenerative Diseases Therapy
Chemical Research in Toxicology, Vol. 31, Núm. 9, pp. 839-842
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Neuroinflammation Signaling Modulated by ASS234, a Multitarget Small Molecule for Alzheimer's Disease Therapy
ACS Chemical Neuroscience, Vol. 9, Núm. 12, pp. 2880-2885
2017
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Corrigendum: Melatonin and nitrones as potential therapeutic agents for stroke [Front. Aging Neurosci., 8 (2016) (281)] DOI:10.3389/fnagi.2016.00281
Frontiers in Aging Neuroscience
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Ischemic brain injury: New insights on the protective role of melatonin
Free Radical Biology and Medicine, Vol. 104, pp. 32-53
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Melatonin as a versatile molecule to design novel multitarget hybrids against neurodegeneration
Future Medicinal Chemistry, Vol. 9, Núm. 8, pp. 765-780
2016
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Melatonin and nitrones as potential therapeutic agents for stroke
Frontiers in Aging Neuroscience, Vol. 8, Núm. NOV
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Melatonin protects against oxygen and glucose deprivation by decreasing extracellular glutamate and Nox-derived ROS in rat hippocampal slices
NeuroToxicology, Vol. 57, pp. 61-68
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Upregulation of Antioxidant Enzymes by ASS234, a Multitarget Directed Propargylamine for Alzheimer's Disease Therapy
CNS Neuroscience and Therapeutics
2014
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Melatonin as potential candidate to prevent the toxicity induced by chemical warfare agents
Archives of Toxicology
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Toxicological and pharmacological evaluation, antioxidant, ADMET and molecular modeling of selected racemic chromenotacrines {11-amino-12-aryl-8,9, 10,12-tetrahydro-7H-chromeno[2,3-b]quinolin-3-ols} for the potential prevention and treatment of Alzheimer's disease
European Journal of Medicinal Chemistry, Vol. 74, pp. 491-501
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Wnt signaling pathway, a potential target for Alzheimer's disease treatment, is activated by a novel multitarget compound ASS234
CNS Neuroscience and Therapeutics
2013
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Toxicity induced by chemical warfare agents: Insights on the protective role of melatonin
Chemico-Biological Interactions, Vol. 206, Núm. 2, pp. 134-142