Publicaciones en las que colabora con Antonio García García (23)

2013

  1. Recent advances in the multitarget-directed ligands approach for the treatment of Alzheimer's disease

    Medicinal Research Reviews, Vol. 33, Núm. 1, pp. 139-189

2011

  1. Effects of novel tacripyrines ITH12117 and ITH12118 on rat vas deferens contractions, calcium transients and cholinesterase activity

    European Journal of Pharmacology, Vol. 660, Núm. 2-3, pp. 411-419

  2. Synthesis, structure, theoretical and experimental in vitro antioxidant/pharmacological properties of α-aryl, N-alkyl nitrones, as potential agents for the treatment of cerebral ischemia

    Bioorganic and Medicinal Chemistry, Vol. 19, Núm. 2, pp. 951-960

2010

  1. Multipotent drugs with cholinergic and neuroprotective properties for the treatment of Alzheimer and neuronal vascular diseases. I. Synthesis, biological assessment, and molecular modeling of simple and readily available 2-aminopyridine-, and 2-chloropyridine-3,5-dicarbonitriles

    Bioorganic and Medicinal Chemistry, Vol. 18, Núm. 16, pp. 5861-5872

  2. Synthesis, inhibitory activity of cholinesterases, and neuroprotective profile of novel 1,8-naphthyridine derivatives

    Journal of Medicinal Chemistry, Vol. 53, Núm. 14, pp. 5129-5143

2009

  1. Tacripyrines, the first tacrine-dihydropyridine hybrids, as multitarget-directed ligands for the treatment of Alzheimer's disease

    Journal of Medicinal Chemistry, Vol. 52, Núm. 9, pp. 2724-2732

2008

  1. New tacrine-dihydropyridine hybrids that inhibit acetylcholinesterase, calcium entry, and exhibit neuroprotection properties

    Bioorganic and Medicinal Chemistry, Vol. 16, Núm. 16, pp. 7759-7769

  2. Synthesis of 6-amino-1,4-dihydropyridines that prevent calcium overload and neuronal death

    European Journal of Medicinal Chemistry, Vol. 43, Núm. 3, pp. 668-674

2007

  1. An update on the pharmacology of galantamine

    Expert Opinion on Investigational Drugs, Vol. 16, Núm. 12, pp. 1987-1998

2006

  1. Intermolecular silyl migration reactions

    Journal of Chemical Research, pp. 698-701

  2. New multipotent tetracyclic tacrines with neuroprotective activity

    Bioorganic and Medicinal Chemistry, Vol. 14, Núm. 24, pp. 8176-8185

  3. Novel multipotent tacrine-dihydropyridine hybrids with improved acetylcholinesterase inhibitory and neuroprotective activities as potential drugs for the treatment of Alzheimer's disease

    Journal of Medicinal Chemistry, Vol. 49, Núm. 26, pp. 7607-7610

  4. Synthesis and biological evaluation of new 4H-pyrano[2,3-b]quinoline derivatives that block acetylcholinesterase and cell calcium signals, and cause neuroprotection against calcium overload and free radicals

    European Journal of Medicinal Chemistry, Vol. 41, Núm. 12, pp. 1464-1469

  5. Synthesis and pharmacology of Galantamine

    Chemical Reviews, Vol. 106, Núm. 1, pp. 116-133

  6. Unexpected results in the Friedländer reaction of 4-aryl-7,7-dimethyl- 5-oxo-5,6,7,8-tetrahydro-4H-[1]benzopyran-3-carbonitriles

    Journal of Chemical Research, pp. 536-538

2005

  1. 1,6-C-H and 1,5-O-Si insertion reactions of alkylidenecarbene derivatives of monosaccharides

    Journal of Carbohydrate Chemistry, Vol. 24, Núm. 4-6, pp. 369-377

  2. Chemical synthesis of galantamine, an acetylcholinesterase inhibitor for treatment of Alzheimer's disease

    Expert Opinion on Therapeutic Patents, Vol. 15, Núm. 5, pp. 575-587

  3. Synthesis, acetylcholinesterase inhibition and neuroprotective activity of new tacrine analogues

    Bioorganic and Medicinal Chemistry, Vol. 13, Núm. 4, pp. 1167-1175

2004

  1. ITH4012 (ethyl 5-amino-6,7,8,9-tetrahydro-2-methyl-4-phenylbenzol[1,8] naphthyridine-3-carboxylate), a novel acetylcholinesterase inhibitor with "calcium promotor" and neuroprotective properties

    Journal of Pharmacology and Experimental Therapeutics, Vol. 310, Núm. 3, pp. 987-994

  2. New classes of AChE inhibitors with additional pharmacological effects of interest for the treatment of Alzheimer's disease

    Current Pharmaceutical Design, Vol. 10, Núm. 25, pp. 3177-3184