Publicaciones en colaboración con investigadores/as de Universitat de València (21)

2007

  1. New antitumoral acetogenin 'Guanacone type' derivatives: Isolation and bioactivity. Molecular dynamics simulation of diacetyl-guanacone

    Bioorganic and Medicinal Chemistry, Vol. 15, Núm. 13, pp. 4369-4381

2006

  1. Guanaconetins, new antitumoral acetogenins, mitochondrial complex I and tumor cell growth inhibitors

    Bioorganic and Medicinal Chemistry, Vol. 14, Núm. 4, pp. 1089-1094

2005

  1. In vitro antitumor structure-activity relationships of threo/trans/threo/ trans/erythro bis-Tetrahydrofuranic acetogenins: Correlations with their inhibition of mitochondrial complex I

    Oncology Research, Vol. 15, Núm. 3, pp. 129-138

2003

  1. In Vitro Antitumor Structure-Activity Relationships of threo/trans/threo mono-Tetrahydrofuranic Acetogenins: Correlations with Their Inhibition of Mitochondrial Complex I

    Oncology Research, Vol. 14, Núm. 3, pp. 147-154

  2. Inhibitory effects on mitochondrial complex I of semisynthetic mono-tetrahydrofuran acetogenin derivatives

    Bioorganic and Medicinal Chemistry Letters, Vol. 13, Núm. 22, pp. 4101-4105

2002

  1. In Vitro Antitumor SAR of threo/cis/threo/cis/erythro bis-THF Acetogenins: Correlations with Their Inhibition of Mitochondrial Complex I

    Oncology Research, Vol. 13, Núm. 12, pp. 521-528

2001

  1. γ-lactone-functionalized antitumoral acetogenins are the most potent inhibitors of mitochondrial complex I

    Bioorganic and Medicinal Chemistry Letters, Vol. 11, Núm. 5, pp. 681-684

2000

  1. Effects of vitamin A deficiency on mitochondrial function in rat liver and heart

    British Journal of Nutrition, Vol. 84, Núm. 6, pp. 927-934

  2. Epoxy-acetogenins and other polyketide epoxy derivatives as inhibitors of the mitochondrial respiratory chain complex I

    Planta Medica, Vol. 66, Núm. 4, pp. 318-323

  3. New evidence for the multiplicity of ubiquinone- and inhibitor-binding sites in the mitochondrial complex I

    Archives of Biochemistry and Biophysics, Vol. 381, Núm. 2, pp. 241-246

  4. Semisynthesis of antitumoral acetogenins: SAR of functionalized alkyl-chain bis-tetrahydrofuranic acetogenins, specific inhibitors of mitochondrial complex I

    Journal of Medicinal Chemistry, Vol. 43, Núm. 25, pp. 4793-4800

  5. Synthesis of N-diisopropyl phosphoryl benzyl-tetrahydroisoquinoline, a new class of mitochondrial complexes I and III inhibitors

    Bioorganic and Medicinal Chemistry Letters, Vol. 10, Núm. 13, pp. 1491-1494

1999

  1. Kinetic characterization of mitochondrial complex I inhibitors using annonaceous acetogenins

    Archives of Biochemistry and Biophysics, Vol. 369, Núm. 1, pp. 119-126

  2. Specific interactions of monotetrahydrofuranic annonaceous acetogenins as inhibitors of mitochondrial complex I

    Chemico-Biological Interactions, Vol. 122, Núm. 3, pp. 171-183

1998

  1. 10-oximeguanacone, the first nitrogenated acetogenin derivative found to be a potent inhibitor of mitochondrial complex I

    Journal of Natural Products, Vol. 61, Núm. 8, pp. 1001-1005

  2. Acetogenins from Annona glabra seeds

    Phytochemistry, Vol. 47, Núm. 5, pp. 811-816

  3. Natural acetogenins from annonaceae, synthesis and mechanisms of action

    Phytochemistry, Vol. 48, Núm. 7, pp. 1087-1117

1997

  1. A deficiency in respiratory complex I in heart mitochondria from vitamin A-deficient rats is counteracted by an increase in coenzyme Q

    Biochemical and Biophysical Research Communications, Vol. 233, Núm. 2, pp. 451-454

  2. Cherimolin-1, new selective inhibitor of the first energy-coupling site of the NADH:ubiquinone oxidoreductase (Complex I)

    Biochemical and Biophysical Research Communications, Vol. 240, Núm. 1, pp. 234-238

  3. Rollimembrin, a novel acetogenin inhibitor of mammalian mitochondrial complex I

    Bioorganic and Medicinal Chemistry Letters, Vol. 7, Núm. 9, pp. 1113-1118