Biología Celular
Departamento
Ana
Martínez
Publicaciones en las que colabora con Ana Martínez (19)
2017
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Biological and Pharmacological Characterization of Benzothiazole-Based CK-1δ Inhibitors in Models of Parkinson's Disease
ACS Omega, Vol. 2, Núm. 8, pp. 5215-5220
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Pharmacological tools based on imidazole scaffold proved the utility of PDE10A inhibitors for Parkinson's disease
Future Medicinal Chemistry, Vol. 9, Núm. 8, pp. 731-748
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Phosphodiesterase7 Inhibition Activates Adult Neurogenesis in Hippocampus and Subventricular Zone In Vitro and In Vivo
Stem Cells, Vol. 35, Núm. 2, pp. 458-472
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Subtly Modulating Glycogen Synthase Kinase 3 β: Allosteric Inhibitor Development and Their Potential for the Treatment of Chronic Diseases
Journal of Medicinal Chemistry, Vol. 60, Núm. 12, pp. 4983-5001
2016
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Small GSK-3 Inhibitor shows efficacy in a motor neuron disease murine model modulating autophagy
PLoS ONE, Vol. 11, Núm. 9
2015
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Morphometric and neurochemical alterations found in l-BMAA treated rats
Environmental Toxicology and Pharmacology, Vol. 39, Núm. 3, pp. 1232-1245
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PDE7 inhibitor TC3.6 ameliorates symptomatology in a model of primary progressive multiple sclerosis
British Journal of Pharmacology, Vol. 172, Núm. 17, pp. 4277-4290
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Phosphodiesterase 7 inhibition induces dopaminergic neurogenesis in hemiparkinsonian rats
Stem Cells Translational Medicine, Vol. 4, Núm. 6, pp. 564-575
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Silencing phosphodiesterase 7B gene by lentiviral-shRNA interference attenuates neurodegeneration and motor deficits in hemiparkinsonian mice
Neurobiology of Aging, Vol. 36, Núm. 2, pp. 1160-1173
2014
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Crosstalk between phosphodiesterase 7 and glycogen synthase kinase-3: Two relevant therapeutic targets for neurological disorders
ACS Chemical Neuroscience, Vol. 5, Núm. 3, pp. 194-204
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Modulation of cAMP-specific PDE without emetogenic activity: New sulfide-like PDE7 inhibitors
Journal of Medicinal Chemistry, Vol. 57, Núm. 20, pp. 8590-8607
2013
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Glycogen synthase kinase-3 inhibitors as potent therapeutic agents for the treatment of Parkinson disease
ACS Chemical Neuroscience, Vol. 4, Núm. 2, pp. 350-360
2012
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5-Imino-1,2,4-thiadiazoles: First small molecules As substrate competitive inhibitors of glycogen synthase kinase 3
Journal of Medicinal Chemistry, Vol. 55, Núm. 4, pp. 1645-1661
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Effect of phosphodiesterase 7 (PDE7) inhibitors in experimental autoimmune encephalomyelitis mice. Discovery of a new chemically diverse family of compounds
Journal of Medicinal Chemistry, Vol. 55, Núm. 7, pp. 3274-3284
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Glycogen synthase kinase 3 inhibition promotes adult hippocampal neurogenesis in vitro and in vivo
ACS Chemical Neuroscience, Vol. 3, Núm. 11, pp. 963-971
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The new iminothiadiazole derivative VP1.14 ameliorates hippocampal damage after an excitotoxic injury
Journal of Neurochemistry, Vol. 122, Núm. 6, pp. 1193-1202
2011
2009
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Anticonvulsant and neuroprotective effects of the novel calcium antagonist NP04634 on kainic acid-induced seizures in rats
Journal of Neuroscience Research, Vol. 87, Núm. 16, pp. 3687-3696
2007
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NP031112, a Thiadiazolidinone compound, prevents inflammation and neurodegeneration under excitotoxic conditions: Potential therapeutic role in brain disorders
Journal of Neuroscience, Vol. 27, Núm. 21, pp. 5766-5776