Bioquímica y Biología Molecular
Departamento
MANUEL ALEJANDRO
ROMERO MARTÍNEZ
Profesor titular de universidad
Publicaciones en las que colabora con MANUEL ALEJANDRO ROMERO MARTÍNEZ (23)
2017
2016
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Melatonin and nitrones as potential therapeutic agents for stroke
Frontiers in Aging Neuroscience, Vol. 8, Núm. NOV
2015
2014
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ITH12410/SC058: A new neuroprotective compound with potential in the treatment of Alzheimer's disease
ACS Chemical Neuroscience, Vol. 5, Núm. 9, pp. 770-775
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Toxicological and pharmacological evaluation, antioxidant, ADMET and molecular modeling of selected racemic chromenotacrines {11-amino-12-aryl-8,9, 10,12-tetrahydro-7H-chromeno[2,3-b]quinolin-3-ols} for the potential prevention and treatment of Alzheimer's disease
European Journal of Medicinal Chemistry, Vol. 74, pp. 491-501
2013
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Nontoxic and neuroprotective β-naphthotacrines for alzheimer's disease
Chemical Research in Toxicology, Vol. 26, Núm. 6, pp. 986-992
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Novel tacrine-related drugs as potential candidates for the treatment of Alzheimer's disease
Bioorganic and Medicinal Chemistry Letters, Vol. 23, Núm. 7, pp. 1916-1922
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Protective effect of creatine against 6-hydroxydopamine-induced cell death in human neuroblastoma SH-SY5Y cells: Involvement of intracellular signaling pathways
Neuroscience, Vol. 238, pp. 185-194
2012
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Galantamine elicits neuroprotection by inhibiting iNOS, NADPH oxidase and ROS in hippocampal slices stressed with anoxia/reoxygenation
Neuropharmacology, Vol. 62, Núm. 2, pp. 1082-1090
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Guanosine protects human neuroblastoma SH-SY5Y cells against mitochondrial oxidative stress by inducing heme oxigenase-1 via PI3K/Akt/GSK-3β pathway
Neurochemistry International, Vol. 61, Núm. 3, pp. 397-404
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Synthesis, biological assessment, and molecular modeling of racemic 7-aryl-9,10,11,12-tetrahydro-7H-benzo[7,8]chromeno[2,3-b]quinolin-8-amines as potential drugs for the treatment of Alzheimer's disease
European Journal of Medicinal Chemistry, Vol. 54, pp. 750-763
2011
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Cholinergic and neuroprotective drugs for the treatment of Alzheimer and neuronal vascular diseases. II. Synthesis, biological assessment, and molecular modelling of new tacrine analogues from highly substituted 2-aminopyridine-3- carbonitriles
Bioorganic and Medicinal Chemistry, Vol. 19, Núm. 1, pp. 122-133
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N-Acylaminophenothiazines: Neuroprotective agents displaying multifunctional activities for a potential treatment of Alzheimer's disease
European Journal of Medicinal Chemistry, Vol. 46, Núm. 6, pp. 2224-2235
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Neuroprotective effect of guanosine against glutamate-induced cell death in rat hippocampal slices is mediated by the phosphatidylinositol-3 kinase/Akt/ glycogen synthase kinase 3β pathway activation and inducible nitric oxide synthase inhibition
Journal of Neuroscience Research, Vol. 89, Núm. 9, pp. 1400-1408
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Neurotoxicity induced by dexamethasone in the human neuroblastoma SH-SY5Y cell line can be prevented by folic acid
Neuroscience, Vol. 190, pp. 346-353
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Neurotoxicity induced by okadaic acid in the human neuroblastoma SH-SY5Y line can be differentially prevented by α7 and β2* nicotinic stimulation
Toxicological Sciences, Vol. 123, Núm. 1, pp. 193-205
2005
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Toxic effects of cadmium on GABA and taurine content in different brain areas of adult male rats
Journal of Physiology and Biochemistry, Vol. 61, Núm. 3, pp. 439-446
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Toxic effects of cadmium on the regulatory mechanism of dopamine and serotonin on prolactin secretion in adult male rats
Toxicology Letters, Vol. 155, Núm. 1, pp. 87-96
2004
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Cadmium exposure differentially modifies the circadian patterns of norepinephrine at the median eminence and plasma LH, FSH and testosterone levels
Toxicology Letters, Vol. 146, Núm. 2, pp. 175-182
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Effect of nitric oxide on prolactin secretion and hypothalamic biogenic amine contents
Life Sciences, Vol. 74, Núm. 13, pp. 1681-1690