Bioquímica y Biología Molecular
Departamento
MARÍA LUZ
LÓPEZ RODRÍGUEZ
Investigadora hasta 2022
Publicaciones en las que colabora con MARÍA LUZ LÓPEZ RODRÍGUEZ (24)
2021
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Isoprenylcysteine Carboxylmethyltransferase-Based Therapy for Hutchinson-Gilford Progeria Syndrome
ACS Central Science, Vol. 7, Núm. 8, pp. 1300-1310
2020
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Glucose metabolism links astroglial mitochondria to cannabinoid effects
Nature, Vol. 583, Núm. 7817, pp. 603-608
2019
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A Potent Isoprenylcysteine Carboxylmethyltransferase (ICMT) Inhibitor Improves Survival in Ras-Driven Acute Myeloid Leukemia
Journal of Medicinal Chemistry, Vol. 62, Núm. 13, pp. 6035-6046
2018
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Development of a Fluorescent Bodipy Probe for Visualization of the Serotonin 5-HT
1A
Receptor in Native Cells of the Immune System
Bioconjugate Chemistry, Vol. 29, Núm. 6, pp. 2021-2027
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A Fluorescent Probe to Unravel Functional Features of Cannabinoid Receptor CB1 in Human Blood and Tonsil Immune System Cells
Bioconjugate Chemistry, Vol. 29, Núm. 2, pp. 382-389
2015
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New inhibitors of angiogenesis with antitumor activity in vivo
Journal of Medicinal Chemistry, Vol. 58, Núm. 9, pp. 3757-3766
2014
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The expression of cannabinoid receptor 1 is significantly increased in atopic patients
Journal of Allergy and Clinical Immunology, Vol. 133, Núm. 3
2013
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New serotonin 5-HT1A receptor agonists endowed with antinociceptive activity in vivo
Journal of Medicinal Chemistry, Vol. 56, Núm. 20, pp. 7851-7861
2011
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New serotonin 5-HT 1A receptor agonists with neuroprotective effect against ischemic cell damage
Journal of Medicinal Chemistry, Vol. 54, Núm. 23, pp. 7986-7999
2007
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Neurochemical effects of the endocannabinoid uptake inhibitor UCM707 in various rat brain regions
Life Sciences, Vol. 80, Núm. 10, pp. 979-988
2006
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Chronic Δ9-tetrahydrocannabinol administration affects serotonin levels in the rat frontal cortex
Naunyn-Schmiedeberg's Archives of Pharmacology, Vol. 372, Núm. 4, pp. 313-317
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UCM707, an inhibitor of the anandamide uptake, behaves as a symptom control agent in models of Huntington's disease and multiple sclerosis, but fails to delay/arrest the progression of different motor-related disorders
European Neuropsychopharmacology, Vol. 16, Núm. 1, pp. 7-18
2004
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Characterization of an anandamide degradation system in prostate epithelial PC-3 cells: Synthesis of new transporter inhibitors as tools for this study
British Journal of Pharmacology, Vol. 141, Núm. 3, pp. 457-467
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Synthesis and structure-activity relationships of a new model of arylpiperazines. Part 7: Study of the influence of lipophilic factors at the terminal amide fragment on 5-HT1A affinity/selectivity
Bioorganic and Medicinal Chemistry, Vol. 12, Núm. 6, pp. 1551-1557
2003
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Optimization of the Pharmacophore Model for 5-HT
7
R Antagonism. Design and Synthesis of New Naphtholactam and Naphthosultam Derivatives
Journal of Medicinal Chemistry, Vol. 46, Núm. 26, pp. 5638-5650
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Design, synthesis and biological evaluation of new endocannabinoid transporter inhibitors
European Journal of Medicinal Chemistry
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Design, synthesis, and biological evaluation of new inhibitors of the endocannabinoid uptake: Comparison with effects on fatty acid amidohydrolase
Journal of Medicinal Chemistry, Vol. 46, Núm. 8, pp. 1512-1522
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Inhibition of fatty acid amidohydrolase, the enzyme responsible for the metabolism of the endocannabinoid anandamide, by analogues of arachidonoyl-serotonin
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol. 18, Núm. 3, pp. 225-231
2002
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Endocannabinoid transporter inhibitors
Current Medicinal Chemistry - Central Nervous System Agents, Vol. 2, Núm. 2, pp. 129-141
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UCM707, a potent and selective inhibitor of endocannabinoid uptake, potentiates hypokinetic and antinociceptive effects of anandamide
European Journal of Pharmacology, Vol. 449, Núm. 1-2, pp. 99-103