Bioquímica y Biología Molecular
Departamento
Wellcome Trust Sanger Institute
Cambridge, Reino UnidoPublicaciones en colaboración con investigadores/as de Wellcome Trust Sanger Institute (9)
2023
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Notch1 mutations drive clonal expansion in normal esophageal epithelium but impair tumor growth
Nature Genetics, Vol. 55, Núm. 2, pp. 232-245
2021
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Mutant clones in normal epithelium outcompete and eliminate emerging tumours
Nature, Vol. 598, Núm. 7881, pp. 510-514
2020
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A single-progenitor model as the unifying paradigm of epidermal and esophageal epithelial maintenance in mice
Nature Communications, Vol. 11, Núm. 1
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Spatial competition shapes the dynamic mutational landscape of normal esophageal epithelium
Nature Genetics, Vol. 52, Núm. 6, pp. 604-614
2019
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Outcompeting p53-Mutant Cells in the Normal Esophagus by Redox Manipulation
Cell Stem Cell, Vol. 25, Núm. 3, pp. 329-341.e6
2018
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Epidermal Tissue Adapts to Restrain Progenitors Carrying Clonal p53 Mutations
Cell Stem Cell, Vol. 23, Núm. 5, pp. 687-699.e8
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Mapping the malaria parasite druggable genome by using in vitro evolution and chemogenomics
Science, Vol. 359, Núm. 6372, pp. 191-199
2017
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Nonenzymatic gluconeogenesis-like formation of fructose 1,6-bisphosphate in ice
Proceedings of the National Academy of Sciences of the United States of America, Vol. 114, Núm. 28, pp. 7403-7407
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Permeability-driven selection in a semi-empirical protocell model: The roots of prebiotic systems evolution
Scientific Reports, Vol. 7, Núm. 1