Bioquímica y Biología Molecular
Departamento
Broad Institute
Cambridge, Estados UnidosPublicaciones en colaboración con investigadores/as de Broad Institute (11)
2023
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Generation of mouse models carrying B cell restricted single or multiplexed loss-of-function mutations through CRISPR-Cas9 gene editing
STAR Protocols, Vol. 4, Núm. 4
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In Vivo Modeling of CLL Transformation to Richter Syndrome Reveals Convergent Evolutionary Paths and Therapeutic Vulnerabilities
Blood cancer discovery, Vol. 4, Núm. 2, pp. 150-169
2021
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Biological significance of monoallelic and biallelic BIRC3 loss in del(11q) chronic lymphocytic leukemia progression
Blood Cancer Journal, Vol. 11, Núm. 7
2020
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CRISPR/Cas9-generated models uncover therapeutic vulnerabilities of del(11q) CLL cells to dual BCR and PARP inhibition
Leukemia, Vol. 34, Núm. 6, pp. 1599-1612
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High throughput single-cell detection of multiplex CRISPR-edited gene modifications
Genome Biology, Vol. 21, Núm. 1
2019
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Mitochondrial Reprogramming Underlies Resistance to BCL-2 Inhibition in Lymphoid Malignancies
Cancer Cell, Vol. 36, Núm. 4, pp. 369-384.e13
2018
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Mapping the malaria parasite druggable genome by using in vitro evolution and chemogenomics
Science, Vol. 359, Núm. 6372, pp. 191-199
2017
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Functional role and therapeutic targeting of p21-activated kinase 4 in multiple myeloma
Blood, Vol. 129, Núm. 16, pp. 2233-2245
2016
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A broad analysis of resistance development in the malaria parasite
Nature Communications, Vol. 7
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Erratum to: Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (Autophagy, 12, 1, 1-222, 10.1080/15548627.2015.1100356
Autophagy
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Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)
Autophagy, Vol. 12, Núm. 1, pp. 1-222