Publikationen, an denen er mitarbeitet Manuela García López (43)

2020

  1. Na+ controls hypoxic signalling by the mitochondrial respiratory chain

    Nature, Vol. 586, Núm. 7828, pp. 287-291

2016

  1. Melatonin protects against oxygen and glucose deprivation by decreasing extracellular glutamate and Nox-derived ROS in rat hippocampal slices

    NeuroToxicology, Vol. 57, pp. 61-68

2015

  1. Both creatine and its product phosphocreatine reduce oxidative stress and afford neuroprotection in an in vitro Parkinson’s model

    ASN Neuro, Vol. 6, Núm. 6

  2. Development of HuperTacrines as non-toxic, cholinesterase inhibitors for the potential treatment of Alzheimer’s disease

    Mini-Reviews in Medicinal Chemistry, Vol. 15, Núm. 8, pp. 648-658

  3. Novel tacrine-grafted ugi adducts as multipotent anti-alzheimer drugs: A synthetic renewal in tacrine-ferulic acid hybrids

    ChemMedChem, Vol. 10, Núm. 3, pp. 523-539

2014

  1. Dibenzo[1,4,5]thiadiazepine: A hardly-known heterocyclic system with neuroprotective properties of potential usefulness in the treatment of neurodegenerative diseases

    European Journal of Medicinal Chemistry, Vol. 81, pp. 350-358

  2. ITH12410/SC058: A new neuroprotective compound with potential in the treatment of Alzheimer's disease

    ACS Chemical Neuroscience, Vol. 5, Núm. 9, pp. 770-775

  3. Isoxazolotacrines as non-toxic and selective butyrylcholinesterase inhibitors for Alzheimer's disease

    Future Medicinal Chemistry, Vol. 6, Núm. 17, pp. 1883-1891

  4. Neuroprotective effect of dimebon against ischemic neuronal damage

    Neuroscience, Vol. 267, pp. 11-21

  5. Neuroprotective effect of melatonin against ischemia is partially mediated by alpha-7 nicotinic receptor modulation and HO-1 overexpression

    Journal of Pineal Research, Vol. 56, Núm. 2, pp. 204-212

  6. New melatonin- N, N -dibenzyl(N -methyl)amine hybrids: Potent neurogenic agents with antioxidant, cholinergic, and neuroprotective properties as innovative drugs for alzheimers disease

    Journal of Medicinal Chemistry, Vol. 57, Núm. 9, pp. 3773-3785

2013

  1. Enantioselective neuroprotective effects of tacripyrine ITH122 against oxygen and glucose deprivation in rat hippocampal slices

    CNS Neuroscience and Therapeutics

  2. Novel multitarget ligand ITH33/IQM9.21 provides neuroprotection in in vitro and in vivo models related to brain ischemia

    Neuropharmacology, Vol. 67, pp. 403-411

  3. PP2A ligand ITH12246 protects against memory impairment and focal cerebral ischemia in mice

    ACS Chemical Neuroscience, Vol. 4, Núm. 9, pp. 1267-1277

  4. Protective effect of creatine against 6-hydroxydopamine-induced cell death in human neuroblastoma SH-SY5Y cells: Involvement of intracellular signaling pathways

    Neuroscience, Vol. 238, pp. 185-194

2012

  1. Galantamine elicits neuroprotection by inhibiting iNOS, NADPH oxidase and ROS in hippocampal slices stressed with anoxia/reoxygenation

    Neuropharmacology, Vol. 62, Núm. 2, pp. 1082-1090

  2. Guanosine protects human neuroblastoma SH-SY5Y cells against mitochondrial oxidative stress by inducing heme oxigenase-1 via PI3K/Akt/GSK-3β pathway

    Neurochemistry International, Vol. 61, Núm. 3, pp. 397-404

2011

  1. Calcium signalling mediated through α7 and non-α7 nAChR stimulation is differentially regulated in bovine chromaffin cells to induce catecholamine release

    British Journal of Pharmacology, Vol. 162, Núm. 1, pp. 94-110

  2. Cholinergic and neuroprotective drugs for the treatment of Alzheimer and neuronal vascular diseases. II. Synthesis, biological assessment, and molecular modelling of new tacrine analogues from highly substituted 2-aminopyridine-3- carbonitriles

    Bioorganic and Medicinal Chemistry, Vol. 19, Núm. 1, pp. 122-133

  3. N-Acylaminophenothiazines: Neuroprotective agents displaying multifunctional activities for a potential treatment of Alzheimer's disease

    European Journal of Medicinal Chemistry, Vol. 46, Núm. 6, pp. 2224-2235