Publicacións nas que colabora con Isabel Iriepa Canalda (10)

2019

  1. Quinoxalinetacrine QT78, a cholinesterase inhibitor as a potential ligand for Alzheimer’s disease therapy

    Molecules, Vol. 24, Núm. 8

2017

  1. 5-Methyl-: N -(8-(5,6,7,8-tetrahydroacridin-9-ylamino)octyl)-5 H -indolo[2,3- b] quinolin-11-amine: A highly potent human cholinesterase inhibitor

    MedChemComm, Vol. 8, Núm. 6, pp. 1307-1317

  2. Multitarget-Directed Ligands Combining Cholinesterase and Monoamine Oxidase Inhibition with Histamine H3R Antagonism for Neurodegenerative Diseases

    Angewandte Chemie - International Edition, Vol. 56, Núm. 41, pp. 12765-12769

2014

  1. Donepezil + propargylamine + 8-hydroxyquinoline hybrids as new multifunctional metal-chelators, ChE and MAO inhibitors for the potential treatment of Alzheimer's disease

    European Journal of Medicinal Chemistry, Vol. 80, pp. 543-561

  2. Structural basis of drugs that increase cardiac inward rectifier Kir2.1 currents

    Cardiovascular Research, Vol. 104, Núm. 2, pp. 337-346

2013

  1. Propafenone blocks human cardiac Kir2.x channels by decreasing the negative electrostatic charge in the cytoplasmic pore

    Biochemical Pharmacology, Vol. 86, Núm. 2, pp. 267-278

2012

  1. Synthesis, biological assessment, and molecular modeling of racemic 7-aryl-9,10,11,12-tetrahydro-7H-benzo[7,8]chromeno[2,3-b]quinolin-8-amines as potential drugs for the treatment of Alzheimer's disease

    European Journal of Medicinal Chemistry, Vol. 54, pp. 750-763

2010

  1. Synthesis, inhibitory activity of cholinesterases, and neuroprotective profile of novel 1,8-naphthyridine derivatives

    Journal of Medicinal Chemistry, Vol. 53, Núm. 14, pp. 5129-5143

2006

  1. Nitric oxide blocks hKv1.5 channels by S-nitrosylation and by a cyclic GMP-dependent mechanism

    Cardiovascular Research, Vol. 72, Núm. 1, pp. 80-89

2003

  1. Effects of irbesartan on cloned potassium channels involved in human cardiac repolarization

    Journal of Pharmacology and Experimental Therapeutics, Vol. 304, Núm. 2, pp. 862-873