Farmacología y Toxicología
Department
Instituto Cajal
Madrid, EspañaPublications in collaboration with researchers from Instituto Cajal (36)
2024
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ApTOLL: A new therapeutic aptamer for cytoprotection and (re)myelination after multiple sclerosis
British Journal of Pharmacology, Vol. 181, Núm. 17, pp. 3263-3281
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Early cortical GABAergic interneurons determine the projection patterns of L4 excitatory neurons
Science Advances, Vol. 10, Núm. 19
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Opposing effects of the purinergic P2X7 receptor on seizures in neurons and microglia in male mice
Brain, Behavior, and Immunity, Vol. 120, pp. 121-140
2023
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Programming of neural progenitors of the adult subependymal zone towards a glutamatergic neuron lineage by neurogenin 2
Stem Cell Reports, Vol. 18, Núm. 12, pp. 2418-2433
2021
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Bcl-2-Assisted Reprogramming of Mouse Astrocytes and Human Fibroblasts into Induced Neurons
Methods in Molecular Biology (Humana Press Inc.), pp. 57-71
2019
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Astrocytic p38α MAPK drives NMDA receptor-dependent long-term depression and modulates long-term memory
Nature Communications, Vol. 10, Núm. 1
2017
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Synapse-specific regulation revealed at single synapses is concealed when recording multiple synapses
Frontiers in Cellular Neuroscience, Vol. 11
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The proof-of-concept of ASS234: Peripherally administered ASS234 enters the central nervous system and reduces pathology in a male mouse model of Alzheimer disease
Journal of Psychiatry and Neuroscience, Vol. 42, Núm. 1, pp. 59-69
2016
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ASS234, as a new multi-target directed propargylamine for Alzheimer's disease therapy
Frontiers in Neuroscience, Vol. 10, Núm. JUN
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Activity-dependent switch of gabaergic inhibition into glutamatergic excitation in astrocyte-neuron networks
eLife, Vol. 5, Núm. DECEMBER2016
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Vascular dysfunction in a transgenic model of Alzheimer's disease: Effects of CB1R and CB2R cannabinoid agonists
Frontiers in Neuroscience, Vol. 10, Núm. SEP
2015
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Preliminary research on 1-(4-bromo-2-nitroimidazol-1-yl)-3-[18F]fluoropropan-2-ol as a novel brain hypoxia PET tracer in a rodent model of stroke
European Journal of Medicinal Chemistry, Vol. 101, pp. 604-615
2014
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Donepezil + propargylamine + 8-hydroxyquinoline hybrids as new multifunctional metal-chelators, ChE and MAO inhibitors for the potential treatment of Alzheimer's disease
European Journal of Medicinal Chemistry, Vol. 80, pp. 543-561
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The JNK inhibitor, SP600125, potentiates the glial response and cell death induced by methamphetamine in the mouse striatum
International Journal of Neuropsychopharmacology, Vol. 17, Núm. 2, pp. 235-246
2013
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Cocaine potentiates MDMA-induced oxidative stress but not dopaminergic neurotoxicity in mice: Implications for the pathogenesis of free radical-induced neurodegenerative disorders
Psychopharmacology, Vol. 230, Núm. 1, pp. 125-135
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Reducing GABAA α5 receptor-mediated inhibition rescues functional and neuromorphological deficits in a mouse model of down syndrome
Journal of Neuroscience, Vol. 33, Núm. 9, pp. 3953-3966
2012
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Dopamine D 1 receptor deletion strongly reduces neurotoxic effects of methamphetamine
Neurobiology of Disease, Vol. 45, Núm. 2, pp. 810-820
2011
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Dopamine D2-receptor knockout mice are protected against dopaminergic neurotoxicity induced by methamphetamine or MDMA
Neurobiology of Disease, Vol. 42, Núm. 3, pp. 391-403
2010
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Lack of adrenomedullin, but not complement factor H, results in larger infarct size and more extensive brain damage in a focal ischemia model
Neuroscience, Vol. 171, Núm. 3, pp. 885-892
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Selective vulnerability in striosomes and in the nigrostriatal dopaminergic pathway after methamphetamine administration : early loss of TH in striosomes after methamphetamine.
Neurotoxicity research, Vol. 18, Núm. 1, pp. 48-58