Publications en collaboration avec des chercheurs de AstraZeneca (United Kingdom) (21)

2024

  1. Trastuzumab deruxtecan in breast cancer

    Critical Reviews in Oncology/Hematology, Vol. 198

2006

  1. The acute and long-term neurotoxic effects of MDMA on marble burying behaviour in mice

    Journal of Psychopharmacology, Vol. 20, Núm. 2, pp. 264-271

2005

  1. Studies on the effect of MDMA ('ecstasy') on the body temperature of rats housed at different ambient room temperatures

    British Journal of Pharmacology, Vol. 146, Núm. 2, pp. 306-312

  2. The role of 5-HT in the impairment of thermoregulation observed in rats administered MDMA ('ecstasy') when housed at high ambient temperature

    Psychopharmacology, Vol. 179, Núm. 4, pp. 884-890

2004

  1. A review of the mechanisms involved in the acute MDMA (ecstasy)-induced hyperthermic response

    European Journal of Pharmacology, Vol. 500, Núm. 1-3 SPEC. ISS., pp. 3-13

  2. Acute and long-term of MDMA on cerebral dopamine biochemistry and function

    Psychopharmacology, Vol. 173, Núm. 3-4, pp. 249-263

  3. Effect of ambient temperature and a prior neurotoxic dose of 3,4-methylenedioxymethamphetamine (MDMA) on the hyperthermic responce of rats to a single or ('binge' ingestion) low of MDMA

    Psychopharmacology, Vol. 173, Núm. 3-4, pp. 264-269

  4. Effect of repeated ('binge') dosing of MDMA to rats housed at normal and high temperature on neurotoxic damage to cerebral 5-HT and dopamine neurones

    Journal of Psychopharmacology, Vol. 18, Núm. 3, pp. 412-416

  5. Hyperthermic and neurotoxic effect of 3,4-methylenedioxymethamphetamine (MDMA) in guinea pigs

    Psychopharmacology

2003

  1. The pharmacology and clinical pharmacology of 3,4-methylenedioxymethamphetamine (MDMA, "ecstasy")

    Pharmacological Reviews, Vol. 55, Núm. 3, pp. 463-508

2001

  1. Studies on the neuroprotective effect of the enantiomers of AR-A008055, a compound structurally related to clomethiazole, on MDMA ("ecstasy")-inducedneurodegeneration in rat brain

    Psychopharmacology, Vol. 157, Núm. 1, pp. 82-88

  2. The mechanisms involved in the long-lasting neuroprotective effect of fluoxetine against MDMA ('ecstasy')-induced degeneration of 5-HT nerve endings in rat brain

    British Journal of Pharmacology, Vol. 134, Núm. 1, pp. 46-57

1997

  1. A study of the neurotoxic effect of MDMA ('ecstasy') on 5-HT neurones in the brains of mothers and neonates following administration of the drug during pregnancy

    British Journal of Pharmacology, Vol. 121, Núm. 4, pp. 827-833

  2. In vivo evidence for free radical involvement in the degeneration of rat brain 5-HT following administration of MDMA ('ecstasy') and p-chloroamphetamine but not the degeneration following fenfluramine

    British Journal of Pharmacology, Vol. 121, Núm. 5, pp. 889-900

1996

  1. The spin trap reagent PBN attenuates degeneration of 5-HT neurones in rat brain induced by p-chloroamphetamine but not fenfluramine

    Neuropharmacology, Vol. 35, Núm. 11, pp. 1615-1620

1995

  1. The hyperthermic and neurotoxic effects of ‘Ecstasy’ (MDMA) and 3,4 methylenedioxyamphetamine (MDA) in the Dark Agouti (DA) rat, a model of the CYP2D6 poor metabolizer phenotype

    British Journal of Pharmacology, Vol. 115, Núm. 7, pp. 1281-1289

  2. The spin trap reagent α-phenyl-N-tert-butylnitrone prevents 'ecstasy'-induced neurodegeneration of 5-hydroxytryptamine neurones

    European Journal of Pharmacology, Vol. 280, Núm. 3, pp. 343-346

1994

  1. A study of the mechanism of MDMA (‘Ecstasy’)‐induced neurotoxicity of 5‐HT neurones using chlormethiazole, dizocilpine and other protective compounds

    British Journal of Pharmacology, Vol. 111, Núm. 1, pp. 131-136

  2. Chlormethiazole and Dizocilpine Block the Behavioural, but Not the Neurotoxic Effects of 5,7‐Dihydroxytryptamine in Mice

    Pharmacology & Toxicology, Vol. 74, Núm. 1, pp. 40-42

1993

  1. 5‐HT loss in rat brain following 3, 4‐methylenedioxymethamphetamine (MDMA), p‐chloroamphetamine and fenfluramine administration and effects of chlormethiazole and dizocilpine

    British Journal of Pharmacology, Vol. 108, Núm. 3, pp. 583-589