Genética, Fisiología y Microbiología
Departament
Raúl
Torres Ruiz
Publicacions en què col·labora amb Raúl Torres Ruiz (15)
2023
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A human genome editing–based MLL::AF4 ALL model recapitulates key cellular and molecular leukemogenic features
Blood, Vol. 142, Núm. 20, pp. 1752-1756
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Comprehensive characterization of a novel, oncogenic and targetable SEPTIN6::ABL2 fusion in T-ALL
British Journal of Haematology
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Expression of HMGCS2 in intestinal epithelial cells is downregulated in inflammatory bowel disease associated with endoplasmic reticulum stress
Frontiers in immunology, Vol. 14, pp. 1185517
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Neuroblastoma RAS viral oncogene homolog (N-RAS) deficiency aggravates liver injury and fibrosis
Cell death & disease, Vol. 14, Núm. 8, pp. 514
2022
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Human-specific changes in two functional enhancers of FOXP2
Cellular and Molecular Biology, Vol. 68, Núm. 11, pp. 16-19
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OGG1 Inhibition Triggers Synthetic Lethality and Enhances The Effect of PARP Inhibitor Olaparib in BRCA1-Deficient TNBC Cells
Frontiers in Oncology, Vol. 12
2021
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Detection of chromosome instability by interphase FISH in mouse and human tissues
STAR Protocols, Vol. 2, Núm. 3
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PD-L1 expression in peripheral T-cell lymphomas is not related to either PD-L1 gene amplification or rearrangements
Leukemia and Lymphoma, Vol. 62, Núm. 7, pp. 1648-1656
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Small molecule inhibitor of OGG1 blocks oxidative DNA damage repair at telomeres and potentiates methotrexate anticancer effects
Scientific Reports, Vol. 11, Núm. 1
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Targeting OGG1 arrests cancer cell proliferation by inducing replication stress
Nucleic Acids Research, Vol. 48, Núm. 21, pp. 12234-12251
2018
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Somatic genome editing with the RCAS-TVA-CRISPR-Cas9 system for precision tumor modeling
Nature Communications, Vol. 9, Núm. 1
2017
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CRISPR-Cas9 technology: Applications and human disease modelling
Briefings in Functional Genomics, Vol. 16, Núm. 1, pp. 4-12
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CRISPR/Cas9 Technology: Applications and Human Disease Modeling
Progress in Molecular Biology and Translational Science (Elsevier B.V.), pp. 23-48
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Modeling Cancer Using CRISPR-Cas9 Technology
Animal Models for the Study of Human Disease: Second Edition (Elsevier Inc.), pp. 905-924
2014
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Engineering human tumour-associated chromosomal translocations with the RNA-guided CRISPR-Cas9 system
Nature Communications, Vol. 5