Genética, Fisiología y Microbiología
Departamento
Centro Nacional de Investigaciones Oncológicas
Madrid, EspañaPublicacións en colaboración con investigadores/as de Centro Nacional de Investigaciones Oncológicas (81)
2024
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Metabolomic profile of neuroendocrine tumors identifies methionine, porphyrin, and tryptophan metabolisms as key dysregulated pathways associated with patient survival
European Journal of Endocrinology, Vol. 190, Núm. 1, pp. 62-74
2023
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A human genome editing–based MLL::AF4 ALL model recapitulates key cellular and molecular leukemogenic features
Blood, Vol. 142, Núm. 20, pp. 1752-1756
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Advances in the Treatment of Gastroenteropancreatic Neuroendocrine Carcinomas: Are we Moving Forward?
Endocrine reviews, Vol. 44, Núm. 4, pp. 724-736
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Comprehensive characterization of a novel, oncogenic and targetable SEPTIN6::ABL2 fusion in T-ALL
British Journal of Haematology
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Expression of HMGCS2 in intestinal epithelial cells is downregulated in inflammatory bowel disease associated with endoplasmic reticulum stress
Frontiers in immunology, Vol. 14, pp. 1185517
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Genomic and immune landscape Of metastatic pheochromocytoma and paraganglioma
Nature Communications, Vol. 14, Núm. 1
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Kras oncogene ablation prevents resistance in advanced lung adenocarcinomas
The Journal of clinical investigation, Vol. 133, Núm. 7
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MicroRNA signature and integrative omics analyses define prognostic clusters and key pathways driving prognosis in patients with neuroendocrine neoplasms
Molecular Oncology, Vol. 17, Núm. 4, pp. 582-597
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Neuroblastoma RAS viral oncogene homolog (N-RAS) deficiency aggravates liver injury and fibrosis
Cell death & disease, Vol. 14, Núm. 8, pp. 514
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The TINCR ubiquitin-like microprotein is a tumor suppressor in squamous cell carcinoma
Nature Communications, Vol. 14, Núm. 1
2022
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A clinically compatible drug-screening platform based on organotypic cultures identifies vulnerabilities to prevent and treat brain metastasis
EMBO molecular medicine, Vol. 14, Núm. 3, pp. e14552
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A faecal microbiota signature with high specificity for pancreatic cancer
Gut, Vol. 71, Núm. 7, pp. 1359-1372
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Activation of the unfolded protein response (Upr) is associated with cholangiocellular injury, fibrosis and carcinogenesis in an experimental model of fibropolycystic liver disease
Cancers, Vol. 14, Núm. 1
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Biallelic germline mutations in MAD1L1 induce a syndrome of aneuploidy with high tumor susceptibility
Science Advances, Vol. 8, Núm. 44
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CRISPR Approaches for the Diagnosis of Human Diseases
International Journal of Molecular Sciences, Vol. 23, Núm. 3
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Human-specific changes in two functional enhancers of FOXP2
Cellular and Molecular Biology, Vol. 68, Núm. 11, pp. 16-19
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OGG1 Inhibition Triggers Synthetic Lethality and Enhances The Effect of PARP Inhibitor Olaparib in BRCA1-Deficient TNBC Cells
Frontiers in Oncology, Vol. 12
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The insecticides permethrin and chlorpyrifos show limited genotoxicity and no leukemogenic potential in human and murine hematopoietic stem progenitor cells
Haematologica
2021
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Aberrant integration of Hepatitis B virus DNA promotes major restructuring of human hepatocellular carcinoma genome architecture
Nature Communications, Vol. 12, Núm. 1
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Alterations in slc4a2, slc26a7 and slc26a9 drive acid–base imbalance in gastric neuroendocrine tumors and uncover a novel mechanism for a co-occurring polyautoimmune scenario
Cells, Vol. 10, Núm. 12