J. Egea-rekin lankidetzan egindako argitalpenak (25)

2023

  1. m-Terphenylamines, Acting as Selective COX-1 Inhibitors, Block Microglia Inflammatory Response and Exert Neuroprotective Activity

    Molecules, Vol. 28, Núm. 14

2021

  1. Analogues of cannabinoids as multitarget drugs in the treatment of Alzheimer's disease

    European Journal of Pharmacology, Vol. 895

2019

  1. Nrf2 plays a protective role against intravascular hemolysis-mediated acute kidney injury

    Frontiers in Pharmacology, Vol. 10

2017

  1. ConBr, A Lectin Purified from the Seeds of Canavalia brasiliensis, Protects Against Ischemia in Organotypic Culture of Rat Hippocampus: Potential Implication of Voltage-Gated Calcium Channels

    Neurochemical Research, Vol. 42, Núm. 2, pp. 347-359

  2. Enzymatic and solid-phase synthesis of new donepezil-based L- and D-glutamic acid derivatives and their pharmacological evaluation in models related to Alzheimer's disease and cerebral ischemia

    European Journal of Medicinal Chemistry, Vol. 130, pp. 60-72

2016

  1. Nrf2-ARE pathway: An emerging target against oxidative stress and neuroinflammation in neurodegenerative diseases

    Pharmacology and Therapeutics, Vol. 157, pp. 84-104

  2. Subthreshold Concentrations of Melatonin and Galantamine Improves Pathological AD-Hallmarks in Hippocampal Organotypic Cultures

    Molecular Neurobiology, Vol. 53, Núm. 5, pp. 3338-3348

  3. The Antioxidant Additive Approach for Alzheimer's Disease Therapy: New Ferulic (Lipoic) Acid Plus Melatonin Modified Tacrines as Cholinesterases Inhibitors, Direct Antioxidants, and Nuclear Factor (Erythroid-Derived 2)-Like 2 Activators

    Journal of Medicinal Chemistry, Vol. 59, Núm. 21, pp. 9967-9973

2015

  1. Alpha7 nicotinic receptor activation protects against oxidative stress via heme-oxygenase i induction

    Biochemical Pharmacology, Vol. 97, Núm. 4, pp. 473-481

  2. Anti-inflammatory role of microglial alpha7 nAChRs and its role in neuroprotection

    Biochemical Pharmacology, Vol. 97, Núm. 4, pp. 463-472

  3. Melatonin-sulforaphane hybrid ITH12674 induces neuroprotection in oxidative stress conditions by a 'drug-prodrug' mechanism of action

    British Journal of Pharmacology, Vol. 172, Núm. 7, pp. 1807-1821

  4. Neuroprotective mechanism of the novel melatonin derivative Neu-P11 in brain ischemia related models

    Neuropharmacology, Vol. 99, pp. 187-195

  5. New melatonin-cinnamate hybrids as multi-target drugs for neurodegenerative diseases: Nrf2-induction, antioxidant effect and neuroprotection

    Future Medicinal Chemistry, Vol. 7, Núm. 15, pp. 1961-1969

  6. The melatonin- N,N-dibenzyl(N-methyl)amine hybrid ITH91/IQM157 affords neuroprotection in an in vitro Alzheimer's model via hemo-oxygenase-1 induction

    ACS Chemical Neuroscience, Vol. 6, Núm. 2, pp. 288-296

2014

  1. Neuroprotective effect of dimebon against ischemic neuronal damage

    Neuroscience, Vol. 267, pp. 11-21

  2. Neuroprotective effect of melatonin against ischemia is partially mediated by alpha-7 nicotinic receptor modulation and HO-1 overexpression

    Journal of Pineal Research, Vol. 56, Núm. 2, pp. 204-212

  3. New 5-unsubstituted dihydropyridines with improved CaV1.3 selectivity as potential neuroprotective agents against ischemic injury

    Journal of Medicinal Chemistry, Vol. 57, Núm. 10, pp. 4313-4323

2013

  1. Identification of 4,6-diaryl-1,4-dihydropyridines as a new class of neuroprotective agents

    MedChemComm, Vol. 4, Núm. 3, pp. 590-594

  2. Novel multitarget ligand ITH33/IQM9.21 provides neuroprotection in in vitro and in vivo models related to brain ischemia

    Neuropharmacology, Vol. 67, pp. 403-411

2012

  1. Benzothiazepine CGP37157 and its isosteric 2′-ethyl analogue provide neuroprotection and block cell calcium entry

    ACS Chemical Neuroscience, Vol. 3, Núm. 7, pp. 519-529