Química en Ciencias Farmacéuticas
Departament
Hospital Universitario de la Princesa
Madrid, EspañaPublicacions en col·laboració amb investigadors/es de Hospital Universitario de la Princesa (57)
2022
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Enantioselective Synthesis and Pharmacological Evaluation of Aza‐CGP37157–Lipoic Acid Hybrids for the Treatment of Alzheimer’s Disease
Antioxidants, Vol. 11, Núm. 1
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Novel Series of Dual NRF2 Inducers and Selective MAO-B Inhibitors for the Treatment of Parkinson’s Disease
Antioxidants, Vol. 11, Núm. 2
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Optical detection of atherosclerosis at molecular level by optical coherence tomography: An in vitro study
Nanomedicine: Nanotechnology, Biology, and Medicine, Vol. 43
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Resveratrol-Based MTDLs to Stimulate Defensive and Regenerative Pathways and Block Early Events in Neurodegenerative Cascades
Journal of Medicinal Chemistry, Vol. 65, Núm. 6, pp. 4727-4751
2021
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Monoamine Oxidase Inhibitors: From Classic to New Clinical Approaches
Handbook of Experimental Pharmacology (Springer Science and Business Media Deutschland GmbH), pp. 229-259
2020
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Antioxidant, anti-inflammatory and neuroprotective profiles of novel 1,4-dihydropyridine derivatives for the treatment of alzheimer’s disease
Antioxidants, Vol. 9, Núm. 8, pp. 1-20
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Aza-CGP37157-lipoic hybrids designed as novel Nrf2-inducers and antioxidants exert neuroprotection against oxidative stress and show neuroinflammation inhibitory properties
Drug Development Research, Vol. 81, Núm. 3, pp. 283-294
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Melatonin-sulforaphane hybrid ITH12674 attenuates glial response in vivo by blocking LPS binding to MD2 and receptor oligomerization
Pharmacological Research, Vol. 152
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NRF2 Regulation Processes as a Source of Potential Drug Targets against Neurodegenerative Diseases
Biomolecules, Vol. 10, Núm. 6
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New Nrf2-inducer compound ITH12674 slows the progression of retinitis pigmentosa in the mouse model rd10
Cellular Physiology and Biochemistry, Vol. 54, Núm. 1, pp. 142-159
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Staphylococcus aureus Prosthetic Joint Infection Is Prevented by a Fluorine- and Phosphorus-Doped Nanostructured Ti–6Al–4V Alloy Loaded With Gentamicin and Vancomycin
Journal of Orthopaedic Research, Vol. 38, Núm. 3, pp. 588-597
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Tuning melatonin receptor subtype selectivity in oxadiazolone-based analogues: Discovery of QR2 ligands and NRF2 activators with neurogenic properties
European Journal of Medicinal Chemistry, Vol. 190
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When it comes to an end: Oxidative stress crosstalk with protein aggregation and neuroinflammation induce neurodegeneration
Antioxidants, Vol. 9, Núm. 8, pp. 1-34
2019
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Molecular Scaffolds as Double-Targeting Agents For the Diagnosis and Treatment of Neuroblastoma
Angewandte Chemie - International Edition, Vol. 58, Núm. 10, pp. 3067-3072
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Nrf2 plays a protective role against intravascular hemolysis-mediated acute kidney injury
Frontiers in Pharmacology, Vol. 10
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Pharmacological doses of melatonin impede cognitive decline in tau-related Alzheimer models, once tauopathy is initiated, by restoring the autophagic flux
Journal of Pineal Research, Vol. 67, Núm. 1
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The angiotensin-(1-7)/Mas receptor axis protects from endothelial cell senescence via klotho and Nrf2 activation
Aging Cell, Vol. 18, Núm. 3
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Urine Aluminum Concentration as a Possible Implant Biomarker of Pseudomonas aeruginosa Infection Using a Fluorine- A nd Phosphorus-Doped Ti-6Al-4V Alloy with Osseointegration Capacity
ACS Omega, Vol. 4, Núm. 7, pp. 11815-11823
2018
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The APPswe/PS1A246E mutations in an astrocytic cell line leads to increased vulnerability to oxygen and glucose deprivation, Ca 2+ dysregulation, and mitochondrial abnormalities
Journal of Neurochemistry, Vol. 145, Núm. 2, pp. 170-182
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MAFG is a potential therapeutic target to restore chemosensitivity in cisplatin-resistant cancer cells by increasing reactive oxygen species
Translational Research, Vol. 200, pp. 1-17