Publikationen, an denen er mitarbeitet María Mercedes Campillo Grau (15)

2019

  1. A Potent Isoprenylcysteine Carboxylmethyltransferase (ICMT) Inhibitor Improves Survival in Ras-Driven Acute Myeloid Leukemia

    Journal of Medicinal Chemistry, Vol. 62, Núm. 13, pp. 6035-6046

2011

  1. Development of non-peptide ligands of growth factor receptor-bound protein 2-src homology 2 domain using molecular modeling and NMR spectroscopy

    Journal of Medicinal Chemistry, Vol. 54, Núm. 4, pp. 1096-1100

  2. The importance of solvation in the design of ligands targeting membrane proteins

    MedChemComm, Vol. 2, Núm. 3, pp. 160-164

2010

  1. Benzimidazole derivatives as new serotonin 5-HT6 receptor antagonists. Molecular mechanisms of receptor inactivation

    Journal of Medicinal Chemistry, Vol. 53, Núm. 3, pp. 1357-1369

2009

  1. Synthesis of new serotonin 5-HT7 receptor ligands. Determinants of 5-ht7/5-ht1a receptor selectivity

    Journal of Medicinal Chemistry, Vol. 52, Núm. 8, pp. 2384-2392

2007

  1. Structural models of class A G protein-coupled receptors as a tool for drug design: Insights on transmembrane bundle plasticity

    Current Topics in Medicinal Chemistry, Vol. 7, Núm. 10, pp. 991-998

  2. The role of internal water molecules in the structure and function of the rhodopsin family of G protein-coupled receptors

    ChemBioChem

2005

  1. A three-dimensional pharmacophore model for 5-hydroxytryptamine6 (5-HT6) receptor antagonists

    Journal of Medicinal Chemistry, Vol. 48, Núm. 13, pp. 4216-4219

  2. Synthesis and structure-activity relationships of a new model of arylpiperazines. 8. Computational simulation of ligand-receptor interaction of 5-HT1AR agonists with selectivity over α1- adrenoceptors

    Journal of Medicinal Chemistry, Vol. 48, Núm. 7, pp. 2548-2558

2003

  1. Optimization of the Pharmacophore Model for 5-HT 7 R Antagonism. Design and Synthesis of New Naphtholactam and Naphthosultam Derivatives

    Journal of Medicinal Chemistry, Vol. 46, Núm. 26, pp. 5638-5650

  2. Benzimidazole derivatives.4. The recognition of the voluminous substituent attached to the basic amino group of 5-HT4 receptor antagonists

    Journal of Computer-Aided Molecular Design, Vol. 17, Núm. 8, pp. 515-524

2002

  1. 5-HT(4) receptor antagonists: structure-affinity relationships and ligand-receptor interactions.

    Current topics in medicinal chemistry, Vol. 2, Núm. 6, pp. 625-641

  2. Benzimidazole derivatives. 3. 3D-QSAR/CoMFA model and computational simulation for the recognition of 5-HT4 receptor antagonists

    Journal of Medicinal Chemistry, Vol. 45, Núm. 22, pp. 4806-4815

2001

  1. 3-D-QSAR/CoMFA and recognition models of benzimidazole derivatives at the 5-HT(4) receptor

    Bioorganic and medicinal chemistry letters, Vol. 11, Núm. 21, pp. 2807-2811

  2. Computational model of the complex between GR113808 and the 5-HT4 receptor guided by site-directed mutagenesis and the crystal structure of rhodopsin

    Journal of Computer-Aided Molecular Design, Vol. 15, Núm. 11, pp. 1025-1033