Química Orgánica
Departamento
JOSÉ ANTONIO
RAMOS ATANCE
Investigador hasta 2020
Publicaciones en las que colabora con JOSÉ ANTONIO RAMOS ATANCE (17)
2013
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New serotonin 5-HT1A receptor agonists endowed with antinociceptive activity in vivo
Journal of Medicinal Chemistry, Vol. 56, Núm. 20, pp. 7851-7861
2011
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New serotonin 5-HT 1A receptor agonists with neuroprotective effect against ischemic cell damage
Journal of Medicinal Chemistry, Vol. 54, Núm. 23, pp. 7986-7999
2007
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Neurochemical effects of the endocannabinoid uptake inhibitor UCM707 in various rat brain regions
Life Sciences, Vol. 80, Núm. 10, pp. 979-988
2006
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Chronic Δ9-tetrahydrocannabinol administration affects serotonin levels in the rat frontal cortex
Naunyn-Schmiedeberg's Archives of Pharmacology, Vol. 372, Núm. 4, pp. 313-317
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UCM707, an inhibitor of the anandamide uptake, behaves as a symptom control agent in models of Huntington's disease and multiple sclerosis, but fails to delay/arrest the progression of different motor-related disorders
European Neuropsychopharmacology, Vol. 16, Núm. 1, pp. 7-18
2004
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Characterization of an anandamide degradation system in prostate epithelial PC-3 cells: Synthesis of new transporter inhibitors as tools for this study
British Journal of Pharmacology, Vol. 141, Núm. 3, pp. 457-467
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Synthesis and structure-activity relationships of a new model of arylpiperazines. Part 7: Study of the influence of lipophilic factors at the terminal amide fragment on 5-HT1A affinity/selectivity
Bioorganic and Medicinal Chemistry, Vol. 12, Núm. 6, pp. 1551-1557
2003
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Optimization of the Pharmacophore Model for 5-HT
7
R Antagonism. Design and Synthesis of New Naphtholactam and Naphthosultam Derivatives
Journal of Medicinal Chemistry, Vol. 46, Núm. 26, pp. 5638-5650
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Design, synthesis and biological evaluation of new endocannabinoid transporter inhibitors
European Journal of Medicinal Chemistry
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Design, synthesis, and biological evaluation of new inhibitors of the endocannabinoid uptake: Comparison with effects on fatty acid amidohydrolase
Journal of Medicinal Chemistry, Vol. 46, Núm. 8, pp. 1512-1522
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Inhibition of fatty acid amidohydrolase, the enzyme responsible for the metabolism of the endocannabinoid anandamide, by analogues of arachidonoyl-serotonin
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol. 18, Núm. 3, pp. 225-231
2002
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Endocannabinoid transporter inhibitors
Current Medicinal Chemistry - Central Nervous System Agents, Vol. 2, Núm. 2, pp. 129-141
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UCM707, a potent and selective inhibitor of endocannabinoid uptake, potentiates hypokinetic and antinociceptive effects of anandamide
European Journal of Pharmacology, Vol. 449, Núm. 1-2, pp. 99-103
2001
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Design, synthesis and biological evaluation of novel arachidonic acid derivatives as highly potent and selective endocannabinoid transporter inhibitors
Journal of Medicinal Chemistry, Vol. 44, Núm. 26, pp. 4505-4508
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Nuevas tendencias en la utilidad terapeútica de los cannabinoides
Anales de Química de la RSEQ, Núm. 2, pp. 14-21
2000
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First pharmacophoric hypothesis for 5-HT
7
antagonism
Bioorganic and Medicinal Chemistry Letters, Vol. 10, Núm. 10, pp. 1097-1100
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Pd(0) amination of benzimidazoles as an efficient method towards new (benzimidazolyl)piperazines with high affinity for the 5-HT(1A) receptor
Tetrahedron, Vol. 56, Núm. 20, pp. 3245-3253