Química Orgánica
Departamento
Centro de Investigaciones Biológicas
Madrid, EspañaPublicaciones en colaboración con investigadores/as de Centro de Investigaciones Biológicas (96)
2024
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Evolution of human H3N2 influenza virus receptor specificity has substantially expanded the receptor-binding domain site
Cell Host and Microbe, Vol. 32, Núm. 2, pp. 261-275.e4
2023
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A tumor-associated heparan sulfate-related glycosaminoglycan promotes the generation of functional regulatory T cells
Cellular and Molecular Immunology, Vol. 20, Núm. 12, pp. 1499-1512
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N′-Phenylacetohydrazide Derivatives as Potent Ebola Virus Entry Inhibitors with an Improved Pharmacokinetic Profile
Journal of Medicinal Chemistry, Vol. 66, Núm. 8, pp. 5465-5483
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Revealing the Specificity of Human H1 Influenza A Viruses to Complex N-Glycans
JACS Au, Vol. 3, Núm. 3, pp. 868-878
2022
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Conformational and Structural Characterization of Carbohydrates and their Interactions Studied by NMR
Current medicinal chemistry, Vol. 29, Núm. 7, pp. 1147-1172
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The Search for Antibacterial Inhibitors Targeting Cell Division Protein FtsZ at Its Nucleotide and Allosteric Binding Sites
Biomedicines, Vol. 10, Núm. 8
2021
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Recent advances in the application of NMR methodologies to analyze the conformation, dynamics, and interactions of saccharides
Carbohydrate Chemistry, Vol. 44, pp. 170-194
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Targeting the FtsZ Allosteric Binding Site with a Novel Fluorescence Polarization Screen, Cytological and Structural Approaches for Antibacterial Discovery
Journal of Medicinal Chemistry, Vol. 64, Núm. 9, pp. 5730-5745
2020
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Fluorinated Carbohydrates as Lectin Ligands: Simultaneous Screening of a Monosaccharide Library and Chemical Mapping by 19F NMR Spectroscopy
Journal of Organic Chemistry, Vol. 85, Núm. 24, pp. 16072-16081
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Structural Basis of Noscapine Activation for Tubulin Binding
Journal of medicinal chemistry, Vol. 63, Núm. 15, pp. 8495-8501
2019
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A Potent Isoprenylcysteine Carboxylmethyltransferase (ICMT) Inhibitor Improves Survival in Ras-Driven Acute Myeloid Leukemia
Journal of Medicinal Chemistry, Vol. 62, Núm. 13, pp. 6035-6046
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Glycosylated Cell-Penetrating Peptides (GCPPs)
ChemBioChem, Vol. 20, Núm. 11, pp. 1400-1409
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Insights into real-time chemical processes in a calcium sensor protein-directed dynamic library
Nature Communications, Vol. 10, Núm. 1
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Self-sterilizing photoactivated catheters to prevent nosocomial infections
Proceedings of SPIE - The International Society for Optical Engineering
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Synthesis, Profiling, and Bioactive Conformation of trans-Cyclopropyl Epothilones
Helvetica Chimica Acta, Vol. 102, Núm. 5
2018
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Avenues to Characterize the Interactions of Extended N-Glycans with Proteins by NMR Spectroscopy: The Influenza Hemagglutinin Case
Angewandte Chemie - International Edition, Vol. 57, Núm. 46, pp. 15051-15055
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Chameleon-like behavior of indolylpiperidines in complex with cholinesterases targets: Potent butyrylcholinesterase inhibitors
European Journal of Medicinal Chemistry, Vol. 145, pp. 431-444
2017
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Breaking the Limits in Analyzing Carbohydrate Recognition by NMR Spectroscopy: Resolving Branch-Selective Interaction of a Tetra-Antennary N-Glycan with Lectins
Angewandte Chemie - International Edition, Vol. 56, Núm. 47, pp. 14987-14991
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Development of a Nucleotide Exchange Inhibitor That Impairs Ras Oncogenic Signaling
Chemistry - A European Journal, Vol. 23, Núm. 7, pp. 1676-1685
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Hidden α-helical propensity segments within disordered regions of the transcriptional activator CHOP
PLoS ONE, Vol. 12, Núm. 12