Sanidad Animal
Departamento
University of Washington
Seattle, Estados UnidosPublicaciones en colaboración con investigadores/as de University of Washington (15)
2024
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An Early Treatment With BKI-1748 Exhibits Full Protection Against Abortion and Congenital Infection in Sheep Experimentally Infected With Toxoplasma gondii
Journal of Infectious Diseases, Vol. 229, Núm. 2, pp. 558-566
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Efficacy of the bumped kinase inhibitor BKI-1708 against the cyst-forming apicomplexan parasites Toxoplasma gondii and Neospora caninum in vitro and in experimentally infected mice
International Journal for Parasitology: Drugs and Drug Resistance, Vol. 25
2021
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Endochin-like quinolones (ELQs) and bumped kinase inhibitors (BKIs): Synergistic and additive effects of combined treatments against Neospora caninum infection in vitro and in vivo
International Journal for Parasitology: Drugs and Drug Resistance, Vol. 17, pp. 92-106
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In vitro activity, safety and in vivo efficacy of the novel bumped kinase inhibitor BKI-1748 in non-pregnant and pregnant mice experimentally infected with Neospora caninum tachyzoites and Toxoplasma gondii oocysts
International Journal for Parasitology: Drugs and Drug Resistance, Vol. 16, pp. 90-101
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One health therapeutics: Target-Based drug development for cryptosporidiosis and other apicomplexa diseases
Veterinary Parasitology, Vol. 289
2020
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Bumped Kinase Inhibitors as therapy for apicomplexan parasitic diseases: lessons learned
International Journal for Parasitology, Vol. 50, Núm. 5, pp. 413-422
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Neospora caninum: Differential proteome of multinucleated complexes induced by the bumped kinase inhibitor BKI-1294
Microorganisms, Vol. 8, Núm. 6
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Neospora caninum: Structure and fate of multinucleated complexes induced by the bumped kinase inhibitor bki-1294
Pathogens, Vol. 9, Núm. 5
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The Impact of BKI-1294 Therapy in Mice Infected With the Apicomplexan Parasite Neospora caninum and Re-infected During Pregnancy
Frontiers in Veterinary Science, Vol. 7
2019
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Treatment with Bumped Kinase Inhibitor 1294 Is Safe and Leads to Significant Protection against Abortion and Vertical Transmission in Sheep Experimentally Infected with Toxoplasma gondii during Pregnancy
Antimicrobial Agents and Chemotherapy, Vol. 63, Núm. 7
2018
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Safety and efficacy of the bumped kinase inhibitor BKI-1553 in pregnant sheep experimentally infected with Neospora caninum tachyzoites
International Journal for Parasitology: Drugs and Drug Resistance, Vol. 8, Núm. 1, pp. 112-124
2017
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Development of a murine vertical transmission model for Toxoplasma gondii oocyst infection and studies on the efficacy of bumped kinase inhibitor (BKI)-1294 and the naphthoquinone buparvaquone against congenital toxoplasmosis
Journal of Antimicrobial Chemotherapy, Vol. 72, Núm. 8, pp. 2334-2341
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In vitro efficacy of bumped kinase inhibitors against Besnoitia besnoiti tachyzoites
International Journal for Parasitology, Vol. 47, Núm. 12, pp. 811-821
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Two novel calcium-dependent protein kinase 1 inhibitors interfere with vertical transmission in mice infected with Neospora caninum tachyzoites
Antimicrobial Agents and Chemotherapy, Vol. 61, Núm. 4
2015
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In vitro and in vivo effects of the bumped kinase inhibitor 1294 in the related cyst-forming apicomplexans Toxoplasma gondii and Neospora caninum
Antimicrobial Agents and Chemotherapy, Vol. 59, Núm. 10, pp. 6361-6374