Instituto Universitario de Investigación en Neuroquímica
Centro/Instituto
![Foto de Jorge](/img/nophoto.png)
Jorge
Manzanares Robles
Publicaciones en las que colabora con Jorge Manzanares Robles (25)
2017
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Disruption of blood–brain barrier integrity in postmortem alcoholic brain: preclinical evidence of TLR4 involvement from a binge-like drinking model
Addiction Biology, Vol. 22, Núm. 4, pp. 1103-1116
2014
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Regulatory role of the cannabinoid CB2 receptor in stress-induced neuroinflammation in mice
British Journal of Pharmacology, Vol. 171, Núm. 11, pp. 2814-2826
2012
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Cannabinoid type 2 receptor activation downregulates stroke-induced classic and alternative brain macrophage/microglial activation concomitant to neuroprotection
Stroke, Vol. 43, Núm. 1, pp. 211-219
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Chronic blockade of cannabinoid CB 2 receptors induces anxiolytic-like actions associated with alterations in GABA A receptors
British Journal of Pharmacology, Vol. 165, Núm. 4, pp. 951-964
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Endogenous cannabinoid system regulates intestinal barrier function in vivo through cannabinoid type 1 receptor activation
American Journal of Physiology - Gastrointestinal and Liver Physiology, Vol. 302, Núm. 5
2011
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Increased vulnerability to 6-hydroxydopamine lesion and reduced development of dyskinesias in mice lacking CB1 cannabinoid receptors
Neurobiology of Aging, Vol. 32, Núm. 4, pp. 631-645
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Regulatory role of cannabinoid receptor 1 in stress-induced excitotoxicity and neuroinflammation
Neuropsychopharmacology, Vol. 36, Núm. 4, pp. 805-818
2005
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Anxiolytic-like effect of a serotonergic ligand with high affinity for 5-HT1A, 5-HT2A and 5-HT3 receptors
European Journal of Pharmacology, Vol. 511, Núm. 1, pp. 9-19
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Synthesis and structure-activity relationships of a new model of arylpiperazines. 8. Computational simulation of ligand-receptor interaction of 5-HT1AR agonists with selectivity over α1- adrenoceptors
Journal of Medicinal Chemistry, Vol. 48, Núm. 7, pp. 2548-2558
2003
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Design and synthesis of S-(-)-2-[[4-(napht-1-yl)piperazin-1-yl]methyl]-1,4-dioxoperhydropyrrolo[1,2- a]pyrazine (CSP-2503) using computational simulation. A 5-HT1A receptor agonist
Bioorganic and Medicinal Chemistry Letters, Vol. 13, Núm. 8, pp. 1429-1432
2002
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Alleviation of motor hyperactivity and neurochemical deficits by endocannabinoid uptake inhibition in a rat model of Huntington's disease
Synapse, Vol. 44, Núm. 1, pp. 23-35
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Cerebrospinal fluid and plasma concentrations of nitric oxide metabolites are increased in dementia with Lewy bodies
Neuroscience Letters, Vol. 333, Núm. 2, pp. 151-153
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Changes in prodynorphin and POMC gene expression in several brain regions of rat fetuses prenatally exposed to Δ9-tetrahydrocannabinol
Neurotoxicity Research, Vol. 4, Núm. 3, pp. 211-218
2001
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Anandamide, but not 2-arachidonoylglycerol, accumulates during in vivo neurodegeneration
Journal of Neurochemistry, Vol. 78, Núm. 6, pp. 1415-1427
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Biochemical, electrophysiological and neurohormonal studies with B-20991, a selective 5-HT1A receptor agonist
Pharmacology, Vol. 62, Núm. 4, pp. 234-242
2000
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Prenatal Δ9-tetrahydrocannabinol exposure modifies proenkephalin gene expression in the fetal rat brain: Sex-dependent differences
Developmental Brain Research, Vol. 120, Núm. 1, pp. 77-81
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Sex steroid influence on cannabinoid CB1 receptor mRNA and endocannabinoid levels in the anterior pituitary gland
Biochemical and Biophysical Research Communications, Vol. 270, Núm. 1, pp. 260-266
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Unilateral 6-hydroxydopamine lesions of nigrostriatal dopaminergic neurons increased CB1 receptor mRNA levels in the caudate-putamen
Life Sciences, Vol. 66, Núm. 6, pp. 485-494
1999
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Identification of endocannabinoids and cannabinoid CB1 receptor mRNA in the pituitary gland
Neuroendocrinology, Vol. 70, Núm. 2, pp. 137-145
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Pharmacological and biochemical interactions between opioids and cannabinoids
Trends in Pharmacological Sciences, Vol. 20, Núm. 7, pp. 287-294