Publicaciones en las que colabora con María José Morcillo Ortega (22)

2005

  1. Synthesis and structure-activity relationships of a new model of arylpiperazines. 8. Computational simulation of ligand-receptor interaction of 5-HT1AR agonists with selectivity over α1- adrenoceptors

    Journal of Medicinal Chemistry, Vol. 48, Núm. 7, pp. 2548-2558

2004

  1. Serotonin 5-HT 7 receptor antagonists

    Current Medicinal Chemistry - Central Nervous System Agents, Vol. 4, Núm. 3, pp. 203-214

  2. Benzimidazole derivatives. Part 5: Design and synthesis of new benzimidazole-arylpiperazine derivatives acting as mixed 5-HT 1A/5-HT 3 ligands

    Bioorganic and Medicinal Chemistry, Vol. 12, Núm. 19, pp. 5181-5191

2003

  1. Optimization of the Pharmacophore Model for 5-HT 7 R Antagonism. Design and Synthesis of New Naphtholactam and Naphthosultam Derivatives

    Journal of Medicinal Chemistry, Vol. 46, Núm. 26, pp. 5638-5650

  2. Design and synthesis of S-(-)-2-[[4-(napht-1-yl)piperazin-1-yl]methyl]-1,4-dioxoperhydropyrrolo[1,2- a]pyrazine (CSP-2503) using computational simulation. A 5-HT1A receptor agonist

    Bioorganic and Medicinal Chemistry Letters, Vol. 13, Núm. 8, pp. 1429-1432

  3. Design and synthesis of new benzimidazole-arylpiperazine derivatives acting as mixed 5-HT1A/5-HT3 ligands

    Bioorganic and Medicinal Chemistry Letters, Vol. 13, Núm. 19, pp. 3177-3180

2002

  1. 5-HT(4) receptor antagonists: structure-affinity relationships and ligand-receptor interactions.

    Current topics in medicinal chemistry, Vol. 2, Núm. 6, pp. 625-641

  2. Arylpiperazine derivatives acting at 5-HT1A receptors

    Current Medicinal Chemistry, Vol. 9, Núm. 4, pp. 443-469

2001

  1. Biochemical, electrophysiological and neurohormonal studies with B-20991, a selective 5-HT1A receptor agonist

    Pharmacology, Vol. 62, Núm. 4, pp. 234-242

2000

  1. Erratum: Corrigendum to 'First pharmacophoric hypothesis for 5-HT 7 antagonism' (Bioorganic and medicinal chemistry letters (2000) 10 (1097) PII: S0960-894X00001669)

    Bioorganic and Medicinal Chemistry Letters

  2. First pharmacophoric hypothesis for 5-HT 7 antagonism

    Bioorganic and Medicinal Chemistry Letters, Vol. 10, Núm. 10, pp. 1097-1100

1999

  1. Benzimidazole derivatives. 2. Synthesis and structure-activity relationships of new azabicyclic benzimidazole-4-carboxylic acid derivatives with affinity for serotoninergic 5-HT3 receptors

    Journal of Medicinal Chemistry, Vol. 42, Núm. 24, pp. 5020-5028

  2. Benzimidazole derivatives. Part 1: Synthesis and structure-activity relationships of new benzimidazole-4-carboxamides and carboxylates as potent and selective 5-HT4 receptor antagonists

    Bioorganic and Medicinal Chemistry, Vol. 7, Núm. 11, pp. 2271-2281

1997

  1. Comparative receptor mapping of serotoninergic 5-HT3 and 5-HT4 binding sites

    Journal of Computer-Aided Molecular Design, Vol. 11, Núm. 6, pp. 589-599

  2. Synthesis and structure-activity relationships of a new model of arylpiperazines. 2. Three-dimensional quantitative structure-activity relationships of hydantoin-phenylpiperazine derivatives with affinity for 5- HT(1A) and α1 receptors. A comparison of CoMFA models

    Journal of Medicinal Chemistry, Vol. 40, Núm. 11, pp. 1648-1656

1996

  1. 1H and 13C NMR spectra of N-ethyl-and N-phenyl-β-carboline-1-carboxamides. Assignments by one- and two-dimensional methods

    Magnetic Resonance in Chemistry, Vol. 34, Núm. 9, pp. 735-737

  2. 2-[4-(o-methoxyphenyl)piperazin-1-ylmethyl]-1,3-dioxoperhydroimidazo[1,5-a] pyridine as a new selective 5-HT1A receptor ligand

    Bioorganic and Medicinal Chemistry Letters, Vol. 6, Núm. 6, pp. 689-694

  3. Novel benzimidazole-4-carboxylic acid derivatives as potent and selective 5-HT3 receptor ligands

    Bioorganic and Medicinal Chemistry Letters, Vol. 6, Núm. 11, pp. 1195-1198

  4. Synthesis and structure-activity relationships of a new model of arylpiperazines. 1. 2-[[4-(o-methoxyphenyl)piperazin-1-yl]methyl]-1,3- dioxoperhydroimidazo[1,5-a]pyridine: A selective 5-HT(1A) receptor agonist

    Journal of Medicinal Chemistry, Vol. 39, Núm. 22, pp. 4439-4450

1995

  1. α1-Adrenoceptor Reagents. Synthesis of Some 5,6,11,11α-Tetrahydro-1H-imidazo[1’,5’: 1,6]pyrido and 5,6,11,11b-Tetrahydro-1H-imidazo-[l’,5’: 1,2] pyrido [3,4-b] indole-1,3(2H)-diones

    Chemical and Pharmaceutical Bulletin, Vol. 43, Núm. 6, pp. 941-946