Instituto Universitario de Investigación en Neuroquímica
Centro/Instituto
![Foto de Tobias](/img/nophoto.png)
Tobias
Engel
Publicaciones en las que colabora con Tobias Engel (11)
2024
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Opposing effects of the purinergic P2X7 receptor on seizures in neurons and microglia in male mice
Brain, Behavior, and Immunity, Vol. 120, pp. 121-140
2018
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MicroRNA-22 controls aberrant neurogenesis and changes in neuronal morphology after status epilepticus
Frontiers in Molecular Neuroscience, Vol. 11
2017
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Expression and function of the metabotropic purinergic P2Y receptor family in experimental seizure models and patients with drug-refractory epilepsy
Epilepsia, Vol. 58, Núm. 9, pp. 1603-1614
2016
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Neurodevelopmental alterations and seizures developed by mouse model of infantile hypophosphatasia are associated with purinergic signalling deregulation
Human Molecular Genetics, Vol. 25, Núm. 19, pp. 4143-4156
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Transient P2X7 receptor antagonism produces lasting reductions in spontaneous seizures and gliosis in experimental temporal lobe epilepsy
Journal of Neuroscience, Vol. 36, Núm. 22, pp. 5920-5932
2015
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MicroRNA targeting of the P2X7 purinoceptor opposes a contralateral epileptogenic focus in the hippocampus
Scientific Reports, Vol. 5
2014
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P2X7 receptor inhibition interrupts the progression of seizures in immature rats and reduces hippocampal damage
CNS Neuroscience and Therapeutics, Vol. 20, Núm. 6, pp. 556-564
2013
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Increased neocortical expression of the P2X7 receptor after status epilepticus and anticonvulsant effect of P2X7 receptor antagonist A-438079
Epilepsia, Vol. 54, Núm. 9, pp. 1551-1561
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P2X receptors as targets for the treatment of status epilepticus
Frontiers in Cellular Neuroscience, Vol. 7, Núm. NOV
2012
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P2X7 receptor in epilepsy; role in pathophysiology and potential targeting for seizure control
International Journal of Physiology, Pathophysiology and Pharmacology, Vol. 4, Núm. 4, pp. 174-187
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Seizure suppression and neuroprotection by targeting the purinergic P2X7 receptor during status epilepticus in mice
FASEB Journal, Vol. 26, Núm. 4, pp. 1616-1628