Publications by the researcher in collaboration with J. Egea (28)

2024

  1. The mitochondrial Na+/Ca2+ exchanger NCLX is implied in the activation of hypoxia-inducible factors

    Redox Biology, Vol. 77

2021

  1. Analogues of cannabinoids as multitarget drugs in the treatment of Alzheimer's disease

    European Journal of Pharmacology, Vol. 895

2020

  1. Na+ controls hypoxic signalling by the mitochondrial respiratory chain

    Nature, Vol. 586, Núm. 7828, pp. 287-291

2018

  1. Folic Acid Protects Against Glutamate-Induced Excitotoxicity in Hippocampal Slices Through a Mechanism that Implicates Inhibition of GSK-3β and iNOS

    Molecular Neurobiology, Vol. 55, Núm. 2, pp. 1580-1589

2017

  1. ConBr, A Lectin Purified from the Seeds of Canavalia brasiliensis, Protects Against Ischemia in Organotypic Culture of Rat Hippocampus: Potential Implication of Voltage-Gated Calcium Channels

    Neurochemical Research, Vol. 42, Núm. 2, pp. 347-359

  2. Mitochondrial complex I deactivation is related to superoxide production in acute hypoxia

    Redox Biology, Vol. 12, pp. 1040-1051

2016

  1. Agmatine, by Improving Neuroplasticity Markers and Inducing Nrf2, Prevents Corticosterone-Induced Depressive-Like Behavior in Mice

    Molecular Neurobiology, Vol. 53, Núm. 5, pp. 3030-3045

  2. Nrf2-ARE pathway: An emerging target against oxidative stress and neuroinflammation in neurodegenerative diseases

    Pharmacology and Therapeutics, Vol. 157, pp. 84-104

  3. Subthreshold Concentrations of Melatonin and Galantamine Improves Pathological AD-Hallmarks in Hippocampal Organotypic Cultures

    Molecular Neurobiology, Vol. 53, Núm. 5, pp. 3338-3348

2015

  1. Agmatine Induces Nrf2 and Protects Against Corticosterone Effects in Hippocampal Neuronal Cell Line

    Molecular Neurobiology, Vol. 51, Núm. 3, pp. 1504-1519

  2. Alpha7 nicotinic receptor activation protects against oxidative stress via heme-oxygenase i induction

    Biochemical Pharmacology, Vol. 97, Núm. 4, pp. 473-481

  3. Anti-inflammatory role of microglial alpha7 nAChRs and its role in neuroprotection

    Biochemical Pharmacology, Vol. 97, Núm. 4, pp. 463-472

  4. Both creatine and its product phosphocreatine reduce oxidative stress and afford neuroprotection in an in vitro Parkinson’s model

    ASN Neuro, Vol. 6, Núm. 6

  5. Melatonin-sulforaphane hybrid ITH12674 induces neuroprotection in oxidative stress conditions by a 'drug-prodrug' mechanism of action

    British Journal of Pharmacology, Vol. 172, Núm. 7, pp. 1807-1821

  6. Microglial HO-1 induction by curcumin provides antioxidant, antineuroinflammatory, and glioprotective effects

    Molecular Nutrition and Food Research, Vol. 59, Núm. 9, pp. 1690-1700

  7. New melatonin-cinnamate hybrids as multi-target drugs for neurodegenerative diseases: Nrf2-induction, antioxidant effect and neuroprotection

    Future Medicinal Chemistry, Vol. 7, Núm. 15, pp. 1961-1969

  8. Positive allosteric modulation of alpha-7 nicotinic receptors promotes cell death by inducing Ca2+ release from the endoplasmic reticulum

    Journal of Neurochemistry, Vol. 133, Núm. 3, pp. 309-319

  9. The melatonin- N,N-dibenzyl(N-methyl)amine hybrid ITH91/IQM157 affords neuroprotection in an in vitro Alzheimer's model via hemo-oxygenase-1 induction

    ACS Chemical Neuroscience, Vol. 6, Núm. 2, pp. 288-296

2014

  1. ITH12410/SC058: A new neuroprotective compound with potential in the treatment of Alzheimer's disease

    ACS Chemical Neuroscience, Vol. 5, Núm. 9, pp. 770-775

2013

  1. Protective effect of creatine against 6-hydroxydopamine-induced cell death in human neuroblastoma SH-SY5Y cells: Involvement of intracellular signaling pathways

    Neuroscience, Vol. 238, pp. 185-194