Instituto Universitario de Investigación en Neuroquímica
Centre/Institute
Hospital Universitario de la Princesa
Madrid, EspañaPublications in collaboration with researchers from Hospital Universitario de la Princesa (65)
2023
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APRIL: A double-blind, placebo-controlled, randomized, Phase Ib/IIa clinical study of ApTOLL for the treatment of acute ischemic stroke
Frontiers in Neurology, Vol. 14
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Safety and Efficacy of ApTOLL in Patients with Ischemic Stroke Undergoing Endovascular Treatment: A Phase 1/2 Randomized Clinical Trial
JAMA Neurology, Vol. 80, Núm. 8, pp. 779-788
2022
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First-in-human phase I clinical trial of a TLR4-binding DNA aptamer, ApTOLL: Safety and pharmacokinetics in healthy volunteers
Molecular Therapy - Nucleic Acids, Vol. 28, pp. 124-135
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The relationship between negative symptoms, social cognition, and social functioning in patients with first episode psychosis
Journal of Psychiatric Research, Vol. 155, pp. 171-179
2021
2020
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Na+ controls hypoxic signalling by the mitochondrial respiratory chain
Nature, Vol. 586, Núm. 7828, pp. 287-291
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The adrenal medulla modulates mechanical allodynia in a rat model of neuropathic pain
International Journal of Molecular Sciences, Vol. 21, Núm. 21, pp. 1-16
2019
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A Neutrophil Timer Coordinates Immune Defense and Vascular Protection
Immunity, Vol. 50, Núm. 2, pp. 390-402.e10
2018
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The APPswe/PS1A246E mutations in an astrocytic cell line leads to increased vulnerability to oxygen and glucose deprivation, Ca 2+ dysregulation, and mitochondrial abnormalities
Journal of Neurochemistry, Vol. 145, Núm. 2, pp. 170-182
2017
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ConBr, A Lectin Purified from the Seeds of Canavalia brasiliensis, Protects Against Ischemia in Organotypic Culture of Rat Hippocampus: Potential Implication of Voltage-Gated Calcium Channels
Neurochemical Research, Vol. 42, Núm. 2, pp. 347-359
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Mitochondrial complex I deactivation is related to superoxide production in acute hypoxia
Redox Biology, Vol. 12, pp. 1040-1051
2016
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Activation of the orphan receptor GPR55 by lysophosphatidylinositol promotes metastasis in triple-negative breast cancer
Oncotarget, Vol. 7, Núm. 30, pp. 47565-47575
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Agmatine, by Improving Neuroplasticity Markers and Inducing Nrf2, Prevents Corticosterone-Induced Depressive-Like Behavior in Mice
Molecular Neurobiology, Vol. 53, Núm. 5, pp. 3030-3045
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Nrf2-ARE pathway: An emerging target against oxidative stress and neuroinflammation in neurodegenerative diseases
Pharmacology and Therapeutics, Vol. 157, pp. 84-104
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Subthreshold Concentrations of Melatonin and Galantamine Improves Pathological AD-Hallmarks in Hippocampal Organotypic Cultures
Molecular Neurobiology, Vol. 53, Núm. 5, pp. 3338-3348
2015
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Alpha7 nicotinic receptor activation protects against oxidative stress via heme-oxygenase i induction
Biochemical Pharmacology, Vol. 97, Núm. 4, pp. 473-481
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Anti-inflammatory role of microglial alpha7 nAChRs and its role in neuroprotection
Biochemical Pharmacology, Vol. 97, Núm. 4, pp. 463-472
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Desarrollo profesional en investigación traslacional en neurociencias y salud mental: educación y formación dentro del Centro de Investigación Biomédica en Red en Salud Mental
Revista de Psiquiatria y Salud Mental, Vol. 8, Núm. 2, pp. 65-74
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Endocannabinoids drive the acquisition of an alternative phenotype in microglia
Brain, Behavior, and Immunity, Vol. 49, pp. 233-245
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Fatty acid synthase is a metabolic marker of cell proliferation rather than malignancy in ovarian cancer and its precursor cells
International Journal of Cancer, Vol. 136, Núm. 9, pp. 2078-2090