Instituto Universitario de Investigación en Neuroquímica
Centro/Instituto
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Instituto de Química Orgánica General
Madrid, EspañaPublicaciones en colaboración con investigadores/as de Instituto de Química Orgánica General (38)
2024
2022
2021
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Use of Radical Oxygen Species Scavenger Nitrones to Treat Oxidative Stress-Mediated Hearing Loss: State of the Art and Challenges
Frontiers in Cellular Neuroscience, Vol. 15
2020
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Tacrine-natural-product hybrids for alzheimer’s disease therapy
Current Medicinal Chemistry, Vol. 27, Núm. 26, pp. 4392-4400
2019
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Donepezil + chromone + melatonin hybrids as promising agents for Alzheimer’s disease therapy
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol. 34, Núm. 1, pp. 479-489
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Synthesis and Neuroprotective Properties of N-Substituted C-Dialkoxyphosphorylated Nitrones
ACS Omega, Vol. 4, Núm. 5, pp. 8581-8587
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Synthesis of new ferulic/lipoic/comenic acid-melatonin hybrids as antioxidants and Nrf2 activators via Ugi reaction
Future Medicinal Chemistry, Vol. 11, Núm. 24, pp. 3097-3108
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Synthesis, antioxidant and Aβ anti-aggregation properties of new ferulic, caffeic and lipoic acid derivatives obtained by the Ugi four-component reaction
Bioorganic Chemistry, Vol. 85, pp. 221-228
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Synthesis, neuroprotective and antioxidant capacity of PBN-related indanonitrones
Bioorganic Chemistry, Vol. 86, pp. 445-451
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Transglycosylation products generated by Talaromyces amestolkiae GH3 β-glucosidases: Effect of hydroxytyrosol, vanillin and its glucosides on breast cancer cells
Microbial Cell Factories, Vol. 18, Núm. 1
2018
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Alzheimer's Disease, the "one-Molecule, One-Target" Paradigm, and the Multitarget Directed Ligand Approach
ACS Chemical Neuroscience, Vol. 9, Núm. 3, pp. 401-403
2017
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Corrigendum: Melatonin and nitrones as potential therapeutic agents for stroke [Front. Aging Neurosci., 8 (2016) (281)] DOI:10.3389/fnagi.2016.00281
Frontiers in Aging Neuroscience
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Development of a Nucleotide Exchange Inhibitor That Impairs Ras Oncogenic Signaling
Chemistry - A European Journal, Vol. 23, Núm. 7, pp. 1676-1685
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New tacrines as anti-alzheimer’s disease agents. The (benzo)chromeno-pyranotacrines
Current Topics in Medicinal Chemistry, Vol. 17, Núm. 31, pp. 3349-3360
2016
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Avarol derivatives as competitive AChE inhibitors, non hepatotoxic and neuroprotective agents for Alzheimer's disease
European Journal of Medicinal Chemistry, Vol. 122, pp. 326-338
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Melatonin and nitrones as potential therapeutic agents for stroke
Frontiers in Aging Neuroscience, Vol. 8, Núm. NOV
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Potent anticholinesterasic and neuroprotective pyranotacrines as inhibitors of beta-amyloid aggregation, oxidative stress and tau-phosphorylation for Alzheimer's disease
European Journal of Medicinal Chemistry, Vol. 118, pp. 178-192
2015
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Pyranopyrazolotacrines as nonneurotoxic, Aβ-anti-aggregating and neuroprotective agents for Alzheimer's disease
Future Medicinal Chemistry, Vol. 7, Núm. 7, pp. 845-855
2014
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Toxicological and pharmacological evaluation, antioxidant, ADMET and molecular modeling of selected racemic chromenotacrines {11-amino-12-aryl-8,9, 10,12-tetrahydro-7H-chromeno[2,3-b]quinolin-3-ols} for the potential prevention and treatment of Alzheimer's disease
European Journal of Medicinal Chemistry, Vol. 74, pp. 491-501
2013
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Nontoxic and neuroprotective β-naphthotacrines for alzheimer's disease
Chemical Research in Toxicology, Vol. 26, Núm. 6, pp. 986-992