Publicaciones en las que colabora con MARÍA LUZ LÓPEZ RODRÍGUEZ (158)

2024

  1. Cancer-Stem-Cell Phenotype-Guided Discovery of a Microbiota-Inspired Synthetic Compound Targeting NPM1 for Leukemia

    JACS Au, Vol. 4, Núm. 5, pp. 1786-1800

2022

  1. 2-(Fluoromethoxy)-4′-(S-methanesulfonimidoyl)-1,1′-biphenyl (UCM-1306), an Orally Bioavailable Positive Allosteric Modulator of the Human Dopamine D1Receptor for Parkinson's Disease

    Journal of Medicinal Chemistry, Vol. 65, Núm. 18, pp. 12256-12272

  2. Discovery of V-0219: A Small-Molecule Positive Allosteric Modulator of the Glucagon-Like Peptide-1 Receptor toward Oral Treatment for "diabesity"

    Journal of Medicinal Chemistry, Vol. 65, Núm. 7, pp. 5449-5461

  3. New Trends in Aging Drug Discovery

    Biomedicines, Vol. 10, Núm. 8

  4. Novel Antagonist of the Type 2 Lysophosphatidic Acid Receptor (LPA2), UCM-14216, Ameliorates Spinal Cord Injury in Mice

    Journal of Medicinal Chemistry, Vol. 65, Núm. 16, pp. 10956-10974

2021

  1. Isoprenylcysteine Carboxylmethyltransferase-Based Therapy for Hutchinson-Gilford Progeria Syndrome

    ACS Central Science, Vol. 7, Núm. 8, pp. 1300-1310

  2. Targeting the FtsZ Allosteric Binding Site with a Novel Fluorescence Polarization Screen, Cytological and Structural Approaches for Antibacterial Discovery

    Journal of Medicinal Chemistry, Vol. 64, Núm. 9, pp. 5730-5745

2020

  1. A Novel Agonist of the Type 1 Lysophosphatidic Acid Receptor (LPA1), UCM-05194, Shows Efficacy in Neuropathic Pain Amelioration

    Journal of Medicinal Chemistry, Vol. 63, Núm. 5, pp. 2372-2390

  2. Glucose metabolism links astroglial mitochondria to cannabinoid effects

    Nature, Vol. 583, Núm. 7817, pp. 603-608

  3. Membrane disruption, but not metabolic rewiring, is the key mechanism of anticancer-action of FASN-inhibitors: a multi-omics analysis in ovarian cancer

    Scientific Reports, Vol. 10, Núm. 1

2019

  1. A Potent Isoprenylcysteine Carboxylmethyltransferase (ICMT) Inhibitor Improves Survival in Ras-Driven Acute Myeloid Leukemia

    Journal of Medicinal Chemistry, Vol. 62, Núm. 13, pp. 6035-6046

  2. Allosteric modulators targeting GPCRs

    GPCRs: Structure, Function, and Drug Discovery (Elsevier), pp. 195-241

  3. Blocking Ras inhibition as an antitumor strategy

    Seminars in Cancer Biology, Vol. 54, pp. 91-100

  4. Essentiality of fatty acid synthase in the 2D to anchorage-independent growth transition in transforming cells

    Nature Communications, Vol. 10, Núm. 1

2018

  1. Development of a Fluorescent Bodipy Probe for Visualization of the Serotonin 5-HT 1A Receptor in Native Cells of the Immune System

    Bioconjugate Chemistry, Vol. 29, Núm. 6, pp. 2021-2027

  2. 2-AG limits Theiler's virus induced acute neuroinflammation by modulating microglia and promoting MDSCs

    GLIA, Vol. 66, Núm. 7, pp. 1447-1463

  3. A Fluorescent Probe to Unravel Functional Features of Cannabinoid Receptor CB1 in Human Blood and Tonsil Immune System Cells

    Bioconjugate Chemistry, Vol. 29, Núm. 2, pp. 382-389

  4. Monoacylglycerol lipase (MAGL) as a promising therapeutic target

    Biochemical Pharmacology, Vol. 157, pp. 18-32

2017

  1. 2-arachidonoylglycerol reduces proteoglycans and enhances remyelination in a progressive model of demyelination

    Journal of Neuroscience, Vol. 37, Núm. 35, pp. 8385-8398

  2. A Positive Allosteric Modulator of the Serotonin 5-HT2C Receptor for Obesity

    Journal of Medicinal Chemistry, Vol. 60, Núm. 23, pp. 9575-9584